Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

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dc.contributor.authorTaştanoğlu, Hüseyin
dc.contributor.authorÇelik, Nurullah
dc.date.accessioned2025-05-04T16:25:07Z
dc.date.available2025-05-04T16:25:07Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: There is a lot of study in adults investigating the Triglyceride-Glucose (Ty-G) index. However, a limited study has been searched in the pediatric age group. Moreover, to the best of our knowledge, there is no study on Turkish children. The aim of this study, to investigate the usability of the triglyceride-glucose index as an indicator of insulin resistance in obese adolescents and to calculate the cut-off values.Method: Six hundred twenty-three pubertal obese adolescents (266 boys, and 357 girls) were retrospectively evaluated. Ty-G index and HOMA-IR levels were calculated. ROC analysis was used for the estimations of the Ty-G index cutoff value.Results: There was positive correlation between HOMA-IR and Ty-G index in boys (r=0.255, p<0.001), in girls (r=0.402, p<0.001), and all study groups (r=0.323, p<0.001). Ty-G index cutoff value for insülin resistance in pubertal obese adolescents was calculated as 8.42 with 70.1 % sensitivity and 59.3 % specificity for all study groups; 8,38 with 71.1 % sensitivity, and 48.3 % specificity for boys; 8,27 with 80% sensitivity, and 52.9% specificity for girls.Conclusions: Ty-G index may be a reliable indicator for insülin resistance in pubertal obese adolescents. More attention should be given fort his marker with prospective studies.
dc.description.abstract[No abstract available]
dc.description.sponsorshipRetrospektif bir çalışma olup destekleyen bir kurum yok
dc.identifier.doi10.7197/cmj.1022934
dc.identifier.doihttps://doi.org/10.7197/cmj.1022934
dc.identifier.endpage363
dc.identifier.issn1305-0028
dc.identifier.issue4
dc.identifier.startpage355
dc.identifier.urihttps://hdl.handle.net/20.500.12418/32726
dc.identifier.volume43
dc.language.isoen
dc.publisherSivas Cumhuriyet University
dc.relation.ispartofCumhuriyet Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250504
dc.subjectInsülin resistance
dc.subjectTriglyceride-Glucose Index
dc.subjectHOMA-IR
dc.subjectObesity
dc.subjectAdolescents
dc.titleTriglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents
dc.typeResearch Article

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