Sivas Cumhuriyet Üniversitesi Kurumsal Akademik Arşivi
DSpace@Cumhuriyet, Sivas Cumhuriyet Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Use of natural deep eutectic solvents for rapid and sensitive extraction of abscisic acid in different food samples prior to spectrophotometric analysis
(Eylül 2024)
This study aimed to develop a cheap and simple sample preparation method with high application potential for
the safe determination of abscisic acid at trace levels in different food samples. In this context, a new sample
preparation method based on ultrasound-assisted natural deep eutectic solvent-based liquid-liquid microextraction
(UA-NADES-LLME) was developed before the spectrophotometric determination of abscisic acid. Four
NADESs were prepared and tested to achieve selective and rapid extraction of abscisic acid from food samples.
Important experimental variables affecting the UA-NADES-LLME method were optimized with a univariate
strategy. The UA-NADES-LLME method has a working range of 15–800 μg L 1 and a detection limit of 4.5 μg L 1
for abscisic acid. The UA-NADES-LLME method provided a preconcentration factor of 250 and an enrichment
factor of 146 for a sample volume of 125 mL. The precision of the UA-NADES-LLME method was investigated by
intraday and interday studies for 30, 300 and 700 μg L 1 concentrations of abscisic acid. As a result of the
studies, the relative standard deviation of the method varied from 1.7 % to 2.8 %. The accuracy of the UANADES-
LLME method was tested with recovery values obtained from standard abscisic acid concentrations
added to food samples. Finally, the UA-NADES-LLME method was applied to the prepared food samples with the
reference method.The results obtained showed that the UA-NADES-LLME method could be successfully applied
to the extraction and determination of abscisic acid in complex matrices.
Investigation of use of hydrophilic/hydrophobic NADESs for selective extraction of As(III) and Sb(III) ions in vegetable samples: Air assisted liquid phase microextraction and chemometric optimization
(Mayıs 2024)
In this paper, a green, cost-effective sample preparation method based on air assisted liquid phase microextraction
(AA-LPME) was developed for the simultaneous extraction of As(III) and Sb(III) ions from vegetable
samples using hydrophilic/hydrophobic natural deep eutectic solvents (NADESs). Central composite design was
used for the optimization of extraction factors including NADES volume, extraction cycle, pH, and curcumin
concentration. Limits of detection for As(III) and Sb(III) were 1.5 ng L 1 and 0.06 ng L 1, respectively. Working
ranges for As(III) and Sb(III) were 0.2–300 ng L 1 (coefficient of determination (R2 = 0.9978) and 5–400 ng L 1
(R2 = 0.9996), respectively. Relative standard deviations for As(III) and Sb(III) were 2.2–2.8% and 2.9–3.2%,
respectively. Enrichment factor of the method was 184 for As(III) and 172 for Sb(III). The accuracy and precision
of the AA-NADES-LPME method were investigated by intraday/interday studies and standard reference material
analysis, respectively. Finally, the AA-NADES-LPME method was successfully applied to microwave digested
vegetable samples using the standard addition approach and acceptable recoveries were achieved.
Evaluation of antioxidant, antimicrobial, enzyme inhibition activity, and cell viability capacity of Hypericum heterophyllum vent., an endemic species in Turkey’s Flora
(Mart 2024)
The aim of this study was determined the antioxidant, antimicrobial, enzyme inhibition activity, and cell
viability capacity of H. heterophyllum (endemic species in the Flora of Turkey) extracts. H. heterophyllum methanolic
extract was used in this study. H. heterophyllum plants collected at the beginning of flowering and during
full flowering. P content was determined with calorimetrically in spectrophotometer. K, CA, Mg, Fe, Mn, Zn and
Cu was determined with Atomic Absorption and N concentration were determined according to the Kjeldahl
distillation method. H. heterophyllum (endemic species in the Flora of Turkey) extract was evaluated for its
antioxidant (DPPH, ABTS, total phenol and flavonoid content), antimicrobial (four bacteria (Escherichia coli,
Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus cereus) and two Candida species (Candida albicans and
Candida tropicalis)), enzyme inhibition activity (ɑ-glucosidase, ɑ-amylase, acetylcholinesterase, butyrylcholinesterase,
tyrosinase), and cell viability (XTT assay) capacity. Extracts from the beginning of flowering period showed
stronger biological activity. It has been determined that the extracts have antioxidant, antibacterial (against
Staphylococcus aureus) anticancer activity (on breast cancer cells), and inhibition effects of BChE and alphaglucosidase.
It has been determined that the extracts obtained from H. heterophylum have important pharmacological
activities, and the plant exhibits higher activity in the BF period. Hypericum heterophyllum Vent. The
activities of the chemicals contained in it against various proteins that are α-gly enzyme (PDB ID: 1R47), AChE
enzyme (PDB ID: 4M0E), BChE enzyme (PDB ID: 5NN0), alpha-Amylase (PDB ID: 3BAJ), breast cancer protein
(PDB ID: 1A52 and 1JNX), were compared. ADME/T analysis of molecules with high activity was performed.
Türkiye'de çalışma hayatından kesitler : işsizlik-sendikal örgütlenme-kadın emeği-işportacılık
(Sivas Cumhuriyet Üniversitesi, 2004)
"Türkiye'de Çalışma Hayatı" ile ilgili kitapta, günümüzde sözü çok edilen küreselleşme, kentleşme, demokratikleşme süreçleri çerçevesinde, içsel ve dışsal faktörlerin de etkilediği birçok konudan sadece dört tanesi ele alınmaktadır. Genç
araştırmacılar tarafından ele alınan bu konular işsizlik ve işsizlik sigortası, sendikal örgütlenme, kadın emeği ve işportacılık gibi konulardır. Dört konudan her biri farklı araştırmacılar tarafından ve konunun gerektirdiği alt başlıklarla ele alınmış ve değerlendirilmiştir. Kitabın "Giriş" bölümü ile son bölümü olan "Türkiye'de Çalışma Hayatı ile İlgili Son Değerlendirme ve Öneriler" bölümü tarafımdan konu bütünlüğü sağlanabilmesi amacıyla yazılmıştır.
Toplumbilim ders notları
(Sivas Cumhuriyet Üniversitesi, 2003) Kocacık, Faruk
"Toplumbilim Ders Notları" adlı kitabın ilk iki baskısı, öğrencilere yönelik olarak ve özet bir biçimde hazırlanmış ve yoğun ilgi görerek kısa sürede tükenmiştir. Üçüncü baskıda bazı düzeltmeler ve eklemeler yer almaktadır. "Toplumbilimin Doğuşu ve Tarihçesi" bölümü biraz genişletilmiş, "Sosyolojide Kuramsal Yaklaşımlar" bölümü eklenmiştir. Aynca güncel konulara örnek oluşturması amacıyla da kitabın sonuna seçilmiş, dört yeni konu -eklenmiştir. Temel toplumsal kurumlar, genelde ayn bir ders olarak okutulduğu için bu kitapta yer almamıştır. Kitabın yeni düzenlemesinde başta Ar. Gör. Fatih Arslan olmak üzere emeği geçen herkese teşekkür eder, kitabın sevgili öğrencilerime ve ilgilenenlere yararlı olmasını dilerim.
