Browsing by Author "Bağda, Efkan"
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BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
Bağda, Efkan; Harmandar, Kevser; Bağda, Esra; Şahin, Gamze; Karakodak, Nurşen; Durmuş, Mahmut; Khezami, Khaoula (Springer, 2021/05/04)In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ... -
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
Khezami, Khaoula; Harmandar, Kevser; Bağda, Esra; Bağda, Efkan; Şahin, Gamze; Karakodak, Nurşen; Durmuş, Mahmut (2021/6)In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ... -
Ecdysozoa Üstşubesi İçin Yeni Bir Moleküler Sinapomorfi: Olası Bir Mitogenomik Transkripsiyon Sinyal Dizisinin Deneysel Olarak Araştırılması
Korkmaz, Ertan Mahir (01/04/2021)Böceklerde mitokondriyal transkripsiyonun başlatılması, ilerlemesi ve sonlanmasında görevli proteinler; POLRMT, TFAM, TFB2M, TFEM ve MTERF (MTERF1, MTERF2, MTERF3, MTERF4, MTERF5) protein ailesi üyeleridir. Bu proteinlerden ... -
Ecdysozoa Üstşubesi İçin Yeni Bir Moleküler Sinapomorfi: Olası Bir Mitogenomik Transkripsiyon Sinyal Dizisinin Deneysel Olarak Araştırılması
Korkmaz, Ertan Mahir (01/04/2021)Böceklerde mitokondriyal transkripsiyonun başlatılması, ilerlemesi ve sonlanmasında görevli proteinler; POLRMT, TFAM, TFB2M, TFEM ve MTERF (MTERF1, MTERF2, MTERF3, MTERF4, MTERF5) protein ailesi üyeleridir. Bu proteinlerden ... -
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
Bağda, Efkan; Bağda, Esra; Durmuş, Mahmut; Yılmaz, Hasan Emre (Elsevier, 2021/11/1)Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ... -
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
Yılmaz, Hasan Emre; Bağda, Efkan; Bağda, Esra; Durmuş, Mahmut (Elsevier, 1 November)Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ... -
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
Bağda, Esra; Bağda, Efkan; Koçak, Abdulkadir; Durmuş, Mahmut (2021/9/15)DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ... -
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
Bağda, Efkan; Bağda, Esra; Koçak, Abdulkadir; Durmuş, Mahmut (Elsevier, 2021/15/09)DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ...