Browsing by Author "Kacan, Selen Baloglu"
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Effect of imatinib on growth of experimental endometriosis in rats
Yildiz, Caglar; Kacan, Turgut; Akkar, Ozlem Bozoklu; Karakus, Savas; Seker, Metin; Kacan, Selen Baloglu; Ozer, Hatice; Cetin, Ali (ELSEVIER SCIENCE BV, 2016)Objective: Currently, medical and surgical treatment options for endometriosis are limited due to suboptimal efficacy, and also safety and tolerance issues. Long-term use of gonadotrophin-releasing hormone analogs, androgenes, ... -
Effects of Pazopanib, Sunitinib, and Sorafenib, Anti-VEGF Agents, on the Growth of Experimental Endometriosis in Rats
Yildiz, Caglar; Kacan, Turgut; Akkar, Ozlem Bozoklu; Karakus, Savas; Kacan, Selen Baloglu; Ozer, Hatice; Cetin, Ali (SAGE PUBLICATIONS INC, 2015)We aimed to compare the effects of pazopanib, sunitinib, and sorafenib on endometriotic tissue morphology and histological characteristics as well as ovarian reserve in a rat model. Experimental endometriosis was established ... -
Investigation of Antitumor Effects of Sorafenib and Lapatinib Alone and in Combination on MCF-7 Breast Cancer Cells
Kacan, Turgut; Altun, Ahmet; Altun, Gulsah Gultekin; Kacan, Selen Baloglu; Sarac, Bulent; Seker, Mehmet Metin; Bahceci, Aykut; Babacan, Nalan (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)Background: Breast cancer evolution and tumor progression are controlled by complex interactions between steroid receptors and growth factor receptor signaling. Aberrant growth factor receptor signaling can augment or ... -
Serum levels of polyamine synthesis enzymes increase in diabetic patients with breast cancer
Celik, V. Kenan; Kapancik, Sercan; Kacan, Turgut; Kacan, Selen Baloglu; Kapancik, Serkan; Kilicgun, Hasan (BIOSCIENTIFICA LTD, 2017)Background: In this study, it was aimed to investigate the relationship between diabetes and breast cancer and the detection of enzymes and ornithine levels in polyamine synthesis pathway in diabetes, breast cancer and ...