Browsing by Author "Pinarbasi, Ergun"
Now showing items 1-12 of 12
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Association between the soluble epoxide hydrolase gene and preeclampsia
Sari, Ismail; Pinarbasi, Hatice; Pinarbasi, Ergun; Yildiz, Caglar (TAYLOR & FRANCIS INC, 2017)Objective: In this study the association between K55R polymorphism, methylation level of the EPHX2 promoter region, and PE was investigated in 520 individuals including 260 PE patients and 260 healthy pregnant women.Methods: ... -
Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women
Pinarbasi, Ergun; Percin, Ferda E.; Yilmaz, Meral; Akgun, Egemen; Cetin, Meral; Cetin, Ali (WILEY, 2007)Aim: To assess the association between human epoxide hydrolase exon 3 and 4 polymorphisms and pre-eclampsia by carrying out a case-control study in Turkish women. Methods: DNA was extracted from peripheral blood leukocytes, ... -
AXIN2 polymorphism and its association with astrocytoma in a Turkish population
Gunes, Emine Gulsen; Pinarbasi, Ergun; Pinarbasi, Hatice (SPANDIDOS PUBL LTD, 2010)The product of AXIN2, a component of Writ signalling, plays a role in tumorigenesis and is dysregulated in cancer cells. In order to determine whether the AXIN2 polymorphism is a risk factor for astrocytoma, we analysed ... -
AXIN2 polymorphism and its association with prostate cancer in a Turkish population
Pinarbasi, Ergun; Gunes, Emine Gulsen; Pinarbasi, Hatice; Donmez, Gonca; Silig, Yavuz (HUMANA PRESS INC, 2011)Polymorphism of AXIN2, a component of Wnt signaling, has been shown to play a role in tumorigenesis and dysregulated in cancer cells. In order to find out if AXIN2 polymorphism is a risk factor for prostate cancer, we ... -
Fibroblast growth factor receptor 4 Gly388Arg polymorphism is not associated with pre-eclampsia in Turkish women
Gunes, Emine Gulsen; Pinarbasi, Ergun (WILEY-BLACKWELL, 2011)Aim: The aim of this study was to assess the association between human fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism and pre-eclampsia (PE) by carrying out a casecontrol study in Turkish women. Materials ... -
FOXP3 rs3761548 polymorphism is associated with knee osteoarthritis in a Turkish population
Cekin, Nilgun; Pinarbasi, Ergun; Bildirici, Aslihan Esra; Donmez, Gonca; Oztemur, Zekeriya; Bulut, Okay; Arslan, Serdal (WILEY, 2018)Aim: Functional polymorphisms located in FOXP3 intron 1 was recently found to be associated with rheumatoid arthritis (RA). Although RA is an autoimmune disease, there is supporting evidence that activated maladaptive ... -
Intracranial arachnoid cyst family with autosomal recessive trait mapped to chromosome 6q22.31-23.2
Bayrakli, Fatih; Okten, Ali Ihsan; Kartal, Ugur; Menekse, Guner; Guzel, Aslan; Oztoprak, Ibrahim; Pinarbasi, Ergun; Kars, Hamit Zafer (SPRINGER WIEN, 2012)Arachnoid cysts are congenital fluid-filled compartments within the cerebrospinal fluid cisterns and cerebral fissures. They most commonly occur sporadically, and familial occurrence has rarely been reported. In this study, ... -
Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women
Percin, Ferda E.; Cetin, Meral; Pinarbasi, Ergun; Akgun, Egemen; Gurlek, Fatma; Cetin, Ali (ELSEVIER SCIENCE BV, 2006)Objectives: It is possible that altered control of aldosterone synthase gene (CYP11B2) expression or translation may be responsible for. hypertension. Hypertension is one of the major components of preeclampsia. We present ... -
MEFV mutations and their relation to major clinical symptoms of Familial Mediterranean Fever
Cekin, Nilgun; Akyurek, Murat Eser; Pinarbasi, Ergun; Ozen, Filiz (ELSEVIER SCIENCE BV, 2017)Familial Mediterranean fever is a common hereditary disease in Turkey. To date, different mutational spectrum of MEFV gene was observed in studies carried out in different regions of Turkey but in most of these studies ... -
Microsomal epoxide hydrolase polymorphisms
Pinarbasi, Hatice; Silig, Yavuz; Pinarbasi, Ergun (SPANDIDOS PUBL LTD, 2010)Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change ... -
A Novel Locus for Restless Legs Syndrome on Chromosome 13q
Balaban, Hatice; Bayrakli, Fatih; Kartal, Ugur; Pinarbasi, Ergun; Topaktas, Suat; Kars, Hamit Zafer (KARGER, 2012)Background: Restless legs syndrome (RLS) is a sensorimotor disorder in which affected individuals suffer from uncomfortable sensations and an urge to move their lower limbs; it occurs mainly in resting situations during ... -
Strong association between lung cancer and the AXIN2 polymorphism
Gunes, Emine Gulsen; Pinarbasi, Ergun; Pinarbasi, Hatice; Silig, Yavuz (SPANDIDOS PUBL LTD, 2009)Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes to carcinogenesis. The effect of the AXIN2 ...