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Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed com pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In
recent years, ...
Experimental and theoretical insights about the effect of some newly designed azomethine group-contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy-
two-membered macroheterocyclic compounds and the investigation of their activity against the neurob-
lastoma cell line. ...
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(Wiley-VCH GmbH, Weinheim, 2021/4)
A new class of cyanopyridine derivatives (10a–e and 11a–e) containing the
phenylurea unit was synthesized and tested against some metabolic enzymes
including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), ...
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 2023/9/28)
We herein report the determination of the cytotoxic activity and expression profiles of
some DNArepair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The
studied novel compounds were ...
Dilay KARADEMİR, Mustafa KARADEMİR, İrem KÜÇÜKYILDIZ, Nazan YURTÇU, İlkin Seda CAN, Esra GÜLTÜRK
(2023/3/3)
Abstract
Amaç: Bu çalışmada amaç epilepsi tanısı almış ve antiepileptik ilaç kullanan gebelerde epilepsi hastalığının ve uygulanan antiepileptik tedavi protokolünün, anne, fetüs ve yenidoğan üzerine etkisinin değerlendi ...
A review of Modular Multilevel Converter for Stationary Applications
(2020)
A modular multilevel converter (MMC) is an advanced voltage source converter applicable to a wide range of medium and high-voltage applications. It has competitive advantages such as quality output performance, high ...
Equilibrium and DFT modeling studies for the biosorption of Safranin O dye from water samples using Bacillus subtilis biosorbent.
(Elsevier, 2023)
Current study deals with the biosorption of Safranin O dye from water by using high potential Bacillus subtilis biosorbent material. The presence of functional groups and surface morphology of biosorbent was analyzed by ...
A series of phenanthroline-imine compounds: Computational, OLED properties and fluorimetric sensing of nitroaromatic compounds.
(Elsevier, 2023)
In this study, Schiff base compounds (1–5) were synthesized by the reaction of 5-amino-1,10-phenanthroline with various aldehydes. The molecular structures of the synthesized compounds were characterized by FT-IR, 1H/13C ...
A Common Complication in Orthopedic Patients: Postoperative Constipation and Related Risk Factors
(2023)
Purpose: The purpose of this study was to determine the frequency of postoperative constipation and risk factors in orthopedic patients.
Design: A descriptive model was used.
Methods: A total of 140 patients who ...
Perinatal and neonatal outcomes of adolescent pregnancies over a 10-year period
(2023;94(6))
Objectives:
Poor overall neonatal outcomes, small neonatal head circumference, neonatal hypoglycemia, need for Neonatal Intensive Care Unit and late-onset neonatal sepsis are more common in adolescents. The aim of this ...