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Structurally diverse heterobimetallic Pb(II)-Salen complexes mechanistic notion of cytotoxic activity against neuroblastoma cancer cell: Synthesis, characterization, protein–ligand interaction profiler, and intuitions from DFT 

Majumdar, Dhrubajyoti; Tüzün, Burak; Pal, Tapan Kumar; Saini, Reena V; Bankura, Kalipada; Mishra, Dipankar (24 Septemb)
In this work, two new heterobimetallic Pb(II) complexes, namely [Zn(L1)(η1-NCS)Pb(η1-SCN)] (1) and [Cd(L2) (η1-NCS)Pb(η1-SCN)]n (2) integrated from Salen ligands (L1/L2) in the presence of NaSCN. The title compounds were ...
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Investigation of structural, electronical and in vitro cytotoxic activity properties of some heterocyclic compounds 

Akkoç, Senem; Tüzün, Burak; Özalp, Ayhan; Kökbudak, Zülbiye (19 July 20)
A series of heterocyclic compounds ( 15 ) were synthesized, characterized and tested towards two human cancer cell lines for learning their in vitro antiproliferative activities. Compound 3 demonstrated the most promising ...
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Synthesis of (4R)-2-(3-hydroxyphenyl)thiazolidine- 4-carboxylic acid substituted phthalocyanines: Anticancer activity on different cancer cell lines and molecular docking studies 

Bilgiçli, Ahmet T.; Bilgicli, Hayriye Genc; Hepokur, Ceylan; Günsel, Armağan; Zengin, Mustafa; Yarasir, M. Nilüfer; Tüzün, Burak (9 March 20)
In this study, firstly, (4R)-2-(3-hydroxyphenyl)thiazolidine-4-carboxylic acid (1) and (4R)-2-(3-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (2) were prepared. Then, the novel type metallophthalocyanines ...
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Cytotoxic effect, spectroscopy, DFT, enzyme inhibition, and moleculer docking studies of some novel mesitylaminopropanols: Antidiabetic and anticholinergics and anticancer potentials 

Tüzün, Burak; Çakmak, Neşe Keklikçioğlu; Tunçbilek, Zuhal; Taş, Ayhan; Taslimi, Parham; Khalilov, Ali N. (09 October)
b-Amino alcohols (2–4) used in this study were re-synthesized in accordance with our previous study. All compounds were characterized by the combination of NMR, UV–Vis, IR experimental and theoretical spectral data. Then, ...



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AuthorTüzün, Burak (4)Akkoç, Senem (1)Bankura, Kalipada (1)Bilgicli, Hayriye Genc (1)Bilgiçli, Ahmet T. (1)... View MoreSubject
DFT (4)
Molecular docking (3)ADME/T (1)anticancer activities (1)b-Amino alcohols (1)... View MoreDate Issued2021 (4)Has File(s)true (4)

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