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Germ-line MTHFR C677T, FV H1299R and PAI-1 5G/4G Variations in Breast Carcinoma
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2013)
Background: Various oncogenes related to cancer have been extensively studied and several polymorphisms have been found to be associated with breast cancer. The current report outlines analysis of germ-line polymorphisms ...
Possible Roles of the Xenobiotic Transporter P-glycoproteins Encoded by the MDR1 3435 C > T Gene Polymorphism in Differentiated Thyroid Cancers
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2013)
Background: P-glycoprotein (Pgp), encoded by the multidrug resistance 1 (MDR1) gene, is an efflux transporter which plays an important role in pharmacokinetics. The current preliminary study was designed to determine ...
The Proto-Oncogene KRAS and BRAF Profiles and Some Clinical Characteristics in Colorectal Cancer in the Turkish Population
(MARY ANN LIEBERT INC, 2013)
Objectives: The aim of the current study was to investigate the prevalence and predictive significance of the KRAS and BRAF mutations in Turkish patients with colorectal cancer (CRC). Methods: Totally, 53 fresh tumoral ...