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Michael/Michael Addition Cascade of 2-Benzylidene-1- indanones with Chalcones: Synthesis and Biological Evaluations of Novel Polycyclic Compounds 

Gezegen,Hayreddin; Tutar, Uğur; Hepokur, Ceylan; Tüzün, Gamze; Atioğlu,Zeliha; Akkurt, Mehmet (2021)
A series of novel racemic 2-aryloyl-1,3-diaryl-2,3,3a,8a-tetrahy drocyclopenta[a]inden-8(1H)-one derivatives were synthesized from KOtBu mediated Michael/Michael addition reaction of 2- benzylidene-1-indanones with ...
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Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether Derivatives and Investigation of Their Cytotoxic Effects 

Alagöz,Mehmet Abdullah; Karakurt,Arzu; Hepokur, Ceylan; Salva, Emine; Önkol, Tijen; Ghoneim, Mohammed M.; Abdelgawad, Mohamed A.; Khames, Ahmed; Kim,Hoon; Mathew,Bijo (2021)
: In this study, 12 new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives were designed and synthesized to investigate their cytotoxic effects. The in vitro cytotoxic activities of the compounds were ...
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Nükleer enerji reaktörleri konferansı 

Ünsal, Derya Betül (Sivas Cumhuriyet Üniversitesi, 2021)
Sivas Cumhuriyet Üniversitesi adına Yenilenebilir Enerji Araştırma Merkezi Tarafından Organize Edilen, Enerji ve Nükleer Reaktörler konferansı, Merkez Müdürü Dr. Öğr. Üyesi Derya Betül ÜNSAL ÇELİMLİ tarafından düzenlendi, ...
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Selective cytotoxicity of paclitaxel bonded silver nanoparticle on different cancer cells 

Danısman-Kalındemirtas¸Ferdane; Kariper, I.Afsin; Hepokur, Ceylan; Erdem-Kuruca,Serap (2021)
Paclitaxel (PTX) is one of the most effective drugs in the treatment of cancer. However, its usability is limited due to low solubility and side effects. In this study, we investigated anticancer effects of PTX bonded ...
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The effects of preoperative fasting on patients undergoing thoracic surgery 

Yılmaz, Meryem; Çelik, Meltem (Elsevier, 2021)
Purpose: The purpose of this study was to determine the effects of fasting before surgery on patients undergoing thoracic surgery. Design: This descriptive cross-sectional study was conducted from January 1 to June 30, ...
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Nanocomposite smart hydrogel based on sepiolite nanochannels/N-isopropyl acrylamide/itaconic acid/acrylamide for invertase immobilization 

Saraydın, Dursun; Öztop,H. Nursevin; Hepokur,Ceylan (2021)
Novel nanocomposite smart hydrogel (NSH) and smart hydrogel (SH) are prepared to be used as a support for invertase. Spectrophotometric and thermal analysis methods were used for the characterization. Lower critical ...
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Synthesis of (4R)-2-(3-hydroxyphenyl)thiazolidine 4-carboxylic acid substituted phthalocyanines: Anticancer activity on different cancer cell lines and molecular docking studies 

Bilgiçli, Ahmet T.; Genc Bilgicli,Hayriye; Hepokur,Ceylan; Tüzün,Burak; Günsel, Armagan; Zengin, Mustafa; Yarasir,M. Nilüfer (2021)
In this study, firstly, (4R)-2-(3-hydroxyphenyl)thiazolidine-4-carboxylic acid (1) and (4R)-2-(3-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (2) were prepared. Then, the novel type metallophthalocyanines ...
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Determination of inhibitor activity of drugs against the COVID-19. 

Gedikli, Mustafa asım; Tüzün, Burak; Sayın, Koray; Ataseven, Hilmi (2021)
Abstract: BACKGROUND: It is the SARS-CoV-2 virus, one of the most significant diseases of today’s world. Due to the high transmission of this disease, studies are ongoing to discover an inhibitor drug that can stop this ...
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The role of perioperative hypothermia in the development of surgical site infection: A systematic review 

Yılmaz, Meryem; Öner Cengiz, Hatice; Uçar, Serpil (Wiley, 2021)
Surgical patients may experience inadvertent perioperative hypothermia, a condition that can cause a variety of complications, including surgical site infection (SSI). The authors of this systematic review used the Preferred ...
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Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies 

Bilgiçli, Ahmet T.; Hepokur, Ceylan; Genc Bilgicli, Hayriye; Tüzün, Burak; Mısır, Sema; Zengina, Mustafa; Yarasir, M. Nilüfer; Günsel, Armağan (2021)
In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyano phenoxy)phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted metallophthalocyanines ...
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AuthorSayın, Koray (18)Altunay, Nail (17)Elik, Adil (15)Tüzün, Burak (14)Kaya Savaş (13)... View MoreSubjectMolecular docking (7)N-heterocyclic carbene (6)I-convergence (5)Wijsman convergence (5)DFT (4)... View MoreDate Issued2021 (402)2020 (19)2022 (3)Has File(s)true (430)

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