dc.contributor.author | Kol, Iclal Ozdemir | |
dc.contributor.author | Kaygusuz, Kenan | |
dc.contributor.author | Gursoy, Sinan | |
dc.contributor.author | Cetin, Ali | |
dc.contributor.author | Kahramanoglu, Zeki | |
dc.contributor.author | Ozkan, Fikret | |
dc.contributor.author | Mimaroglu, Caner | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:14:02Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:14:02Z | |
dc.date.issued | 2009 | |
dc.identifier.issn | 1011-8934 | |
dc.identifier.issn | 1598-6357 | |
dc.identifier.uri | https://dx.doi.org/10.3346/jkms.2009.24.5.883 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/10045 | |
dc.description | WOS: 000270520300019 | en_US |
dc.description | PubMed ID: 19794988 | en_US |
dc.description.abstract | We designed a randomized, double-blinded study to determine the efficacy and safety of 0.5 mg/kg intravenous ephedrine for the prevention of hypotension during spinal anesthesia for cesarean delivery. Patients were randomly allocated into two groups: ephedrine group (n=21) and control group (n=21). Intravenous preload of 15 mL/kg lactated Ringer's solution was given. Shortly after the spinal injection, ephedrine 0.5 mg/kg or saline was injected intravenous for 60 sec. The mean of highest and lowest heart rate in the ephedrine group was higher than those of control group (P<0.05). There were significant lower incidences of hypotension and nausea and vomiting in the ephedrine group compared with the control group (8 [38.1%] vs. 18 [85.7%]); (4 [19%] vs. 12 [57.1%], respectively) (P<0.05). The first rescue ephedrine time in the ephedrine group was significantly longer (14.9 +/- 7.1 min vs. 7.9 +/- 5.4 min) than that of the control group (P<0.05). Neonatal outcome were similar between the study groups. These findings suggest, the prophylactic bolus dose of 0.5 mg/kg intravenous ephedrine given at the time of intrathecal block after a crystalloid fluid preload, plus rescue boluses reduce the incidence of hypotension. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | en_US |
dc.relation.isversionof | 10.3346/jkms.2009.24.5.883 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Anesthesia, Spinal | en_US |
dc.subject | Cesarean Section | en_US |
dc.subject | Ephedrine | en_US |
dc.subject | Hypotension | en_US |
dc.title | The Effects of Intravenous Ephedrine During Spinal Anesthesia for Cesarean Delivery: A Randomized Controlled Trial | en_US |
dc.type | article | en_US |
dc.relation.journal | JOURNAL OF KOREAN MEDICAL SCIENCE | en_US |
dc.contributor.department | [Kol, Iclal Ozdemir] Cumhuriyet Univ, Dept Anesthesiol, Fac Med, Sch Med, TR-58140 Sivas, Turkey -- [Cetin, Ali] Cumhuriyet Univ, Dept Obstet & Gynecol, Sch Med, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | Cetin, Ali -- 0000-0002-5767-7894 | en_US |
dc.identifier.volume | 24 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.endpage | 888 | en_US |
dc.identifier.startpage | 883 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |