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dc.contributor.authorTandogan, Izzet
dc.contributor.authorAslan, Halil
dc.contributor.authorAksoy, Yuksel
dc.contributor.authorTopal, Ergun
dc.contributor.authorTurgut, Okan
dc.contributor.authorYilmaz, Ahmet
dc.contributor.authorAcikgoz, Nusret
dc.contributor.authorKosar, Feridun
dc.contributor.authorOzdemir, Ramazan
dc.descriptionWOS: 000241971900006en_US
dc.descriptionPubMed ID: 17047446en_US
dc.description.abstractObjective The aim of this study was to assess the effect of coronary collateral circulation (CCC) on QT dispersion (QTD) in coronary artery disease. Background A prolonged QTD has been linked to increased heterogeneity of ventricular repolarization implicated in the genesis of ventricular arrhythmias and has been associated with an adverse prognosis in patients with coronary artery disease. Method CCC and corrected QTD (QTcD) were established in patients who had at least 85% stenosis in the left anterior descending coronary artery or in proximal part or in the body of the right coronary artery. Furthermore, left ventricular function score was determined for all the patients. Results While CCC was not present (CCC grade 0) in 32 patients, 68 patients were observed with CCC (CCC grade >= 1). Mean QTcD was higher in patients who had CCC grade >= 1 than in patients with grade 0 (64.3 +/- 3.5 and 46.8 +/- 2.7, respectively, P= 0.002). We detected a significant correlation between the collateral score and QTcD (r=0.354, P=0.001). CCC grade,: 1 patients had higher mean left ventricular function scores than grade 0 patients (P=0.048). Left ventricular function score and QTcD were observed to be correlated (r=0.200, P=0.046). Conclusion CCC in chronic coronary artery disease was not established to have a positive decreasing effect on QTcD. On the contrary, QTcD values were observed to be even higher in patients with well developed CCC. Further research including larger series and long-term follow-up is required to investigate this issue.en_US
dc.subjectcoronary artery diseaseen_US
dc.subjectcoronary collateral circulationen_US
dc.subjectventricular arrhythmiasen_US
dc.titleImpact of coronary collateral circulation on QT dispersion in patients with coronary artery diseaseen_US
dc.relation.journalCORONARY ARTERY DISEASEen_US
dc.contributor.departmentCumhuriyet Univ, Fac Med, Dept Cardiol, TR-58100 Sivas, Turkey -- Inonu Univ, Fac Med, Dept Cardiol, Malatya, Turkeyen_US
dc.contributor.authorIDTurgut, Okan -- 0000-0002-6847-3029en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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