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dc.contributor.authorSokmen, A
dc.contributor.authorVardar-Unlu, G
dc.contributor.authorPolissiou, M
dc.contributor.authorDaferera, D
dc.contributor.authorSokmen, M
dc.contributor.authorDonmez, E
dc.descriptionWOS: 000186378400003en_US
dc.descriptionPubMed ID: 14595577en_US
dc.description.abstractThe essential oil, obtained by Clevenger distillation, and water-soluble and water-insoluble parts of the methanol extracts of Achillea sintenisii Hub. Mor. were individually assayed for their antimicrobial activities against 12 bacteria and two yeasts, Candida albicans and C. krusei. No activity was exhibited by the water-soluble subtraction, whereas both the water-insoluble subfraction of the methanol extracts and the essential oil were found to be active against some test microorganisms studied. Since the essential oil possessed stronger activity than the other extracts tested, it was further fractionated and the fractions were evaluated for their antimicrobial activity, followed by GC-MS analysis, resulting in the identification of 32 compounds which constituted 90.2% of the total oil. The GC-MS analysis of the oil and its fractions revealed that the main components of the oil, e.g. camphor and eucalyptol, possessed appreciable activity against C. albicans and Clostridium Perfringens. The findings presented here also suggest that the other constituents of the oil, e.g. borneol and piperitone can also be taken into account for the activity observed. Copyright (C) 2003 John Wiley Sons, Ltd.en_US
dc.publisherJOHN WILEY & SONS LTDen_US
dc.subjectAchillea sintenisiien_US
dc.subjectessential oilen_US
dc.subjectantimicrobial activityen_US
dc.titleAntimicrobial activity of essential oil and methanol extracts of Achillea sintenisii Hub. Mor. (Asteraceae)en_US
dc.relation.journalPHYTOTHERAPY RESEARCHen_US
dc.contributor.departmentCumhuriyet Univ, Fac Sci & Literature, Dept Biol, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Fac Med, Dept Microbiol, TR-58140 Sivas, Turkey -- Agr Univ Athens, Lab Gen Chem, Athens 11855, Greece -- Cumhuriyet Univ, Fac Sci & Literature, Dept Chem, TR-58140 Sivas, Turkeyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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