Show simple item record

dc.contributor.authorCandan, F
dc.contributor.authorUnlu, M
dc.contributor.authorTepe, B
dc.contributor.authorDaferera, D
dc.contributor.authorPolissiou, M
dc.contributor.authorSokmen, A
dc.contributor.authorAkpulat, HA
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:23:24Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:23:24Z
dc.date.issued2003
dc.identifier.issn0378-8741
dc.identifier.urihttps://dx.doi.org/10.1016/S0378-8741(03)00149-1
dc.identifier.urihttps://hdl.handle.net/20.500.12418/11360
dc.descriptionWOS: 000184438300014en_US
dc.descriptionPubMed ID: 12860311en_US
dc.description.abstractThe in vitro antimicrobial and antioxidant activities of the essential oil and methanol extracts of Achillea millefolium subsp. millefollium Afan. (Asteraceae) were investigated. GC-MS analysis of the essential oil resulted in the identification of 36 compounds constituting 90.8% of the total oil. Eucalyptol. camphor, alpha-terpineol, beta-pinene, and borneol were the principal components comprising 60.7% of the oil. The oil strongly reduced the diphenylpicrylhydrazyl radical (IC50 = 1.56 mug/ml) and exhibited hydroxyl radical scavenging effect in the Fe3+-EDTA-H2O2 deoxyribose system (IC50 = 2.7 mug/ml). It also inhibited the nonenzymatic lipid peroxidation of rat liver homogenate (IC50 = 13.5 mug/ml). The polar phase of the extract showed antioxidant activity. The oil showed antimicrobial activity against Streptococcus pneumoniae, Clostridium perfringens, Candida albicans, Mycobacterium smegmatis, Acinetobacter lwoffii and Candida krusei while water-insoluble parts of the methanolic extracts exhibited slight or no activity. This study confirms that the essential oil of Achillea millefolium possesses antioxidant and antimicrobial properties in vitro. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherELSEVIER SCI IRELAND LTDen_US
dc.relation.isversionof10.1016/S0378-8741(03)00149-1en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAchillea millefoliumen_US
dc.subjectantioxidant activityen_US
dc.subjectantimicrobial activityen_US
dc.subjectmethanol extractsen_US
dc.subjectessential oilen_US
dc.subjectGC-MSen_US
dc.titleAntioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp millefolium Afan. (Asteraceae)en_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF ETHNOPHARMACOLOGYen_US
dc.contributor.departmentCumhuriyet Univ, Fac Sci & Literature, Dept Chem, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Fac Med, Dept Microbiol, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Fac Sci & Literature, Dept Biol, TR-58140 Sivas, Turkey -- Agr Univ Athens, Lab Gen Chem, Athens 11855, Greeceen_US
dc.contributor.authorIDTEPE, Bektas -- 0000-0001-8982-5188; Akpulat, Huseyin Askin -- 0000-0001-8394-2746en_US
dc.identifier.volume87en_US
dc.identifier.issue02.Maren_US
dc.identifier.endpage220en_US
dc.identifier.startpage215en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record