dc.contributor.author | Silig, Y | |
dc.contributor.author | Ozdemir, O | |
dc.contributor.author | Atalay, A | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:23:36Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:23:36Z | |
dc.date.issued | 2003 | |
dc.identifier.issn | 0301-1208 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/11400 | |
dc.description | WOS: 000182735400008 | en_US |
dc.description | PubMed ID: 22900302 | en_US |
dc.description.abstract | Liver and colon pro- and anti-oxidant enzyme activities were investigated in rats treated with ethyl nitrosourea (ENU) (i.p.) (4 mg/kg body wt) for 6 months. The pro-oxidant enzymes (NADPH cytochrome c reductase, NADH cytochrome c reductase, NADH cytochrome b(5) reductase and cytochrome P-4502E1 and the antioxidant enzyme, superoxide dismutase (SOD) exhibited significantly increased activity in liver and colon. Glucose-6-phosphate dehydrogenase (G6PDH) and glutathione-S-transferase (GST) showed enhanced activity in liver, but decreased activity in colon. Glutathione peroxidase (GP) and glutathione reductase (GR) activities were significantly increased in colon, but decreased in liver. Catalase (CAT) activity while showed a significant increase in liver, exhibited only marginal increase in colon. Malondialdehyde (MDA) level was significantly elevated in both tissues. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | NATL INST SCIENCE COMMUNICATION | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.title | Liver and colon pro- and anti-oxidant enzyme activities in rats after long-term ethylnitrosourea exposure | en_US |
dc.type | article | en_US |
dc.relation.journal | INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS | en_US |
dc.contributor.department | Cumhuriyet Univ, Fac Sci & Arts, Dept Chem, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Fac Med, Dept Med Biol, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Fac Med, Dept Biochem & Genet, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | ATALAY, Ali Ihsan -- 0000-0002-7379-9082 | en_US |
dc.identifier.volume | 40 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 138 | en_US |
dc.identifier.startpage | 136 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |