dc.contributor.author | Arici, MK | |
dc.contributor.author | Arici, DS | |
dc.contributor.author | Topalkara, A | |
dc.contributor.author | Guler, C | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:25:24Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:25:24Z | |
dc.date.issued | 2000 | |
dc.identifier.issn | 1442-6404 | |
dc.identifier.uri | https://dx.doi.org/10.1046/j.1442-9071.2000.00237.x | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/11694 | |
dc.description | WOS: 000090031900008 | en_US |
dc.description | PubMed ID: 10933774 | en_US |
dc.description.abstract | Purpose: This study was designed to determine the effect of long-term antiglaucoma topical medication on the ocular surface; measuring basal Schirmer's and tear break-up time tests using conjunctival impression cytology. Methods: The ocular surfaces of 30 control subjects (group 1), 24 primary open-angle glaucoma patients treated with 0.5% betaxolol hydrochloride (group 2), 27 primary open-angle glaucoma patients treated with 0.5% timolol maleate (group 3) and 26 primary open-angle glaucoma patients treated with 0.5% betaxolol and 1% dipivefrin hydrochloride (group 4) were evaluated. Basal Schirmer's and tear break-up time tests were measured and ocular surface changes were determined by impression cytology. Impression cytology specimens of each group were graded and scored in the range 0-3 according to Nelson's method. Results: Patients in groups 2, 3 and 4 showed statistically significant fewer normal basal Schirmer's tests (wettability) and tear break-up time tests (P < 0.01). Also, the conjunctival impression cytology scores were significantly higher in groups 2, 3 and 4 than in group 1 (P < 0.01). Conclusions: The conclusion was that it is possible that conjunctival surface and tear film function change after the long-term use of antiglaucoma medication. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | BLACKWELL SCIENCE ASIA | en_US |
dc.relation.isversionof | 10.1046/j.1442-9071.2000.00237.x | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | antiglaucoma drugs | en_US |
dc.subject | impression cytology | en_US |
dc.subject | Schirmer's test | en_US |
dc.subject | tear break-up time test | en_US |
dc.title | Adverse effects of topical antiglaucoma drugs on the ocular surface | en_US |
dc.type | article | en_US |
dc.relation.journal | CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | en_US |
dc.contributor.department | Cumhuriyet Univ, Sch Med, Dept Ophthalmol, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Sch Med, Dept Pathol, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | arici, mustafa kemal -- 0000-0002-6350-9723 | en_US |
dc.identifier.volume | 28 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 117 | en_US |
dc.identifier.startpage | 113 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |