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In vitro swelling studies and preliminary biocompatibility evaluation of acrylamide-based hydrogels

Date

1996

Author

Karadag, E
Saraydin, D
Cetinkaya, S
Guven, O

Metadata

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Abstract

In this in vitro study, the biocompatibility of acrylamide-based hydrogels such as acrylamide/crotonic and acrylamide/itaconic acid, prepared by using gamma-rays, has been investigated against some biochemical parameters of human serum. The swelling kinetics of acrylamide/crotonic and acrylamide/itaconic acid hydrogels are investigated in distilled water and physiological saline solution-and some swelling and diffusion parameters have been calculated. For the analysis of biocompatibility, acrylamide/crotonic and acrylamide/itaconic acid hydrogels are incubated in 10 different human sera for 24 h and their biocompatibilities with some biochemical parameters have been investigated. No significant difference in values before and after the test procedures have been found. It is therefore concluded that acrylamide/crotonic and acrylamide/itaconic acid hydrogels are biocompatible.

Source

BIOMATERIALS

Volume

17

Issue

1

URI

https://dx.doi.org/10.1016/0142-9612(96)80757-5
https://hdl.handle.net/20.500.12418/11890

Collections

  • Makale Koleksiyonu [5200]
  • Makale Koleksiyonu [5745]
  • Öksüz Yayınlar Koleksiyonu - WoS [6162]



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