dc.contributor.author | ALTINOZ, S | |
dc.contributor.author | OZER, D | |
dc.contributor.author | TEMIZER, A | |
dc.contributor.author | YUKSEL, N | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:38:51Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:38:51Z | |
dc.date.issued | 1994 | |
dc.identifier.issn | 0003-2654 | |
dc.identifier.uri | https://dx.doi.org/10.1039/an9941901575 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/11936 | |
dc.description | WOS: A1994NZ70100026 | en_US |
dc.description | PubMed ID: 7943747 | en_US |
dc.description.abstract | Differential-pulse adsorptive stripping voltammetry was used to determine ceftriaxone in serum and aqueous humour samples. The method involved extraction of the ceftriaxone from serum samples with an Amberlite XAD-2 column followed by elution with methanol. The recovery was 97.6% with a relative standard deviation of 3.3% at a ceftriaxone concentration of 90.9 mu g l(-1). Peak currents of ceftriaxone were measured with a hanging mercury drop electrode at -0.78 V versus an Ag-AgCl reference electrode in pH 3.0 Britton-Robinson buffer. The calibration graph was linear from 0.02 to 1300 mu g l(-1). The method was applied to cataract cases and ceftriaxone levels were measured in aqueous humour and serum samples from patients who had received 1 or 2 g of ceftriaxone intravenously. Aqueous humour was added to the polarographic cell directly. The amounts of ceftriaxone in the aqueous humour and serum samples with respect to time were measured. The pharmacokinetic profiles for 1 and 2 g were compared. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ROYAL SOC CHEMISTRY | en_US |
dc.relation.isversionof | 10.1039/an9941901575 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | CEFTRIAXONE DETERMINATION | en_US |
dc.subject | DIFFERENTIAL-PULSE ADSORPTIVE STRIPPING VOLTAMMETRY | en_US |
dc.subject | AQUEOUS HUMOR | en_US |
dc.subject | SERUM | en_US |
dc.title | DETERMINATION OF CEFTRIAXONE IN AQUEOUS-HUMOR AND SERUM SAMPLES BY DIFFERENTIAL-PULSE ADSORPTIVE STRIPPING VOLTAMMETRY | en_US |
dc.type | article | en_US |
dc.relation.journal | ANALYST | en_US |
dc.contributor.department | HACETTEPE UNIV,FAC PHARM,DEPT ANALYT CHEM,ANKARA 06100,TURKEY -- CUMHURIYET UNIV,FAC MED,DEPT OPHTHALMOL,SIVAS 58040,TURKEY | en_US |
dc.identifier.volume | 119 | en_US |
dc.identifier.issue | 7 | en_US |
dc.identifier.endpage | 1577 | en_US |
dc.identifier.startpage | 1575 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |