dc.contributor.author | GOKALP, AS | |
dc.contributor.author | TOKSOY, HB | |
dc.contributor.author | TURKAY, S | |
dc.contributor.author | BAKICI, MZ | |
dc.contributor.author | KAYA, R | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:38:51Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:38:51Z | |
dc.date.issued | 1994 | |
dc.identifier.issn | 0009-9228 | |
dc.identifier.uri | https://dx.doi.org/10.1177/000992289403300607 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/11940 | |
dc.description | WOS: A1994NR58100007 | en_US |
dc.description | PubMed ID: 8200169 | en_US |
dc.description.abstract | The purpose of this study was to determine the role of intravenous immunoglobulin (IVIG) administration in preterm neonates with S. typhimurium infection. A randomized trial of 47 preterm neonates with intestinal or extraintestinal S. tymphimurium infection was performed. Neonates were randomly divided into two groups: 22 neonates were only given cefoperazone (group 1); 25 neonates were given cefoperazone plus IVIG (group 2). IVIG was given at a dose of 500 mg/kg on da)is 1, 2, 3, and 8 after entry into the study. Following treatment, bacteremia, complications, mortality rate, recovery time, and duration of antimicrobial therapy were evaluated in two groups. Bacteremia was found in 31.4% in group 1 and 8% in group 2 (P<.05); complications developed in 81.8% in group 1 and 16% in group 2 (P<0.01); mortality was 40.9% in group 1 and 12% in group 2 (P<.05). Recovery took 15 days in group 1 and 8 days in group 2 (P<.01). The duration of antimicrobial therapy was 20 days in group 1 and 1 1 days in group 2 (P<.01). We conclude that IVIG treatment in combination with antibiotics in preterm neonates with S. typhimurium infection reduces the complications, mortality rate, and duration of therapy. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | WESTMINSTER PUBL INC | en_US |
dc.relation.isversionof | 10.1177/000992289403300607 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.title | INTRAVENOUS IMMUNOGLOBULIN IN THE TREATMENT OF SALMONELLA-TYPHIMURIUM INFECTIONS IN PRETERM NEONATES | en_US |
dc.type | article | en_US |
dc.relation.journal | CLINICAL PEDIATRICS | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.endpage | 352 | en_US |
dc.identifier.startpage | 349 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |