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Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents
(26 May 202)
Various novel heterocyclic compounds containing pyrimidine nuclei
5H-chromeno[4,3-d]pyrimidine (4a–c, e–h, l–r, t) and pyrimidine-5-yl-(2-
hydroxyphenyl)methanone (5a, c, d, f–k, m–o, r, s, u) were synthesized
from the ...
Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies
(5th Octobe)
In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyanophenoxy)
phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted
metallophthalocyanines ...
Octa-substituted Zinc(II), Cu(II), and Co(II) phthalocyanines with 1-(4-hydroxyphenyl)propane- 1-one: Synthesis, sensitive protonation behaviors, Ag(I) induced H-type aggregation properties, antibacterial– antioxidant activity, and molecular docking studies
(18 June 20)
This study shows the synthesis and characterization of 4,5-bis(4-propionylphenoxy)
phthalonitrile (2) and its octa-substituted phthalocyanine
derivatives [ZnPc(3), CuPc(4), and CoPc(5)]. A combination of standard
spectroscopic ...
Synthesis and docking calculations of tetrafluoronaphthalene derivatives and their inhibition profiles against some metabolic enzymes
(5 February)
Syntheses of tetrahydroepoxy, O‐allylic, O‐prenylic, and O‐propargylic tetrafluoronaphthalene
derivatives, starting from 1‐bromo‐2,3,4,5,6‐pentafluorobenzene,
are reported here for the first time. The O‐substituted ...