Evaluating the Implant Stability of Titanium Prepared Platelet Rich Fibrin Treated Peri- implant Osseous Defects with Resonance Frequency Analysis

Abstract

Objective: In this study, we aimed to examine the efficiency and the effect of TitaniumPlatelet-Rich Fibrin (T-PRF), which which can be used in guided bone regeneration, and its early period regeneration capacity on implant stability. Methods: Twelve male New Zealand white rabbits were used for this study.each of the right and left tibias of rabbits Using a trephine bur (diameter 7.0 mm), monocortical defects were prepared (7 mm width,4 mm depth).Subsequently, dental implants(AL-Technology dental implants sharkimplants) were installed into the left and right tibia (diameter 3.0 mm, length 8 mm). In the experimental groups, the peri-implant defect was filled respectively 1-autogenous grafts, 2-T-PRF 3-synthetic grafts (MIS 4BONE ). The control was left in an unfilled state. Implant stability was evaluated with the resonance frequency analysis method (RFA). Results: The Ostell ISQ for the experimental groups respectively 1 -autogenous graft group 76.00±3.89,2-T-PRF group 75.00±3.84,3- sentetic graft group 67.00±5.72 while control group 56,33±5,12.The difference between the 2 groups (autogenous graft and prf groups) was statistically not significant while all other differences between groups are statistically significant. Conclusion: Within the limits of this study, it was found that periimplantal defects in the regeneration of T-PRF is effective as the autogenous bone graft.We believed that T-PRF can be used guided bone regenerationand guided tissue regeneration as autogenic matrix in the future

Objective: In this study, we aimed to examine the efficiency and the effect of TitaniumPlatelet-Rich Fibrin (T-PRF), which which can be used in guided bone regeneration, and its early period regeneration capacity on implant stability. Methods: Twelve male New Zealand white rabbits were used for this study.each of the right and left tibias of rabbits Using a trephine bur (diameter 7.0 mm), monocortical defects were prepared (7 mm width,4 mm depth).Subsequently, dental implants(AL-Technology dental implants sharkimplants) were installed into the left and right tibia (diameter 3.0 mm, length 8 mm). In the experimental groups, the peri-implant defect was filled respectively 1-autogenous grafts, 2-T-PRF 3-synthetic grafts (MIS 4BONE ). The control was left in an unfilled state. Implant stability was evaluated with the resonance frequency analysis method (RFA). Results: The Ostell ISQ for the experimental groups respectively 1 -autogenous graft group 76.00±3.89,2-T-PRF group 75.00±3.84,3- sentetic graft group 67.00±5.72 while control group 56,33±5,12.The difference between the 2 groups (autogenous graft and prf groups) was statistically not significant while all other differences between groups are statistically significant. Conclusion: Within the limits of this study, it was found that periimplantal defects in the regeneration of T-PRF is effective as the autogenous bone graft.We believed that T-PRF can be used guided bone regenerationand guided tissue regeneration as autogenic matrix in the future