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Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure
(BMC, 2016)
Substantial attention and resources have been directed to improving outcomes of patients with critical illnesses, in particular sepsis, but all recent clinical trials testing various interventions or strategies have failed ...
Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper
(ELSEVIER IRELAND LTD, 2016)
Levosimendan is a positive inotrope with vasodilating properties (inodilator) indicated for decompensated heart failure (HF) patients with low cardiac output. Accumulated evidence supports several pleiotropic effects of ...
Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance
(SPRINGER, 2016)
Purpose: Acute heart failure (AHF) causes high burden of mortality, morbidity, and repeated hospitalizations worldwide. This guidance paper describes the tailored treatment approaches of different clinical scenarios of AHF ...
Biosafety standards for working with Crimean-Congo hemorrhagic fever virus
(MICROBIOLOGY SOC, 2016)
In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus, CCHF virus (CCHFV), is classified as a hazard group 4 agent and handled in containment level (CL)-4. In contrast, most endemic ...
Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Lung cancer is one of the most common mortal cancer types both for men and women. Several different biomarkers have been analyzed to reveal lung cancer prognosis pathways for developing efficient therapeutics and diagnostic ...
Emergency management of severe hyperkalemia: Guideline for best practice and opportunities for the future
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2016)
Hyperkalemia is a common electrolyte disorder, especially in chronic kidney disease, diabetes mellitus, or heart failure. Hyperkalemia can lead to potentially fatal cardiac dysrhythmias, and it is associated with increased ...
Bone quality and quantity measurement techniques in dentistry
(2016)
In dentistry, finding a reliable method for measurement mineral density of bone and bone strength in jaw bones is not only beneficial for implant planning, but also benefical in early diagnosis of diseases which effects ...
Micronutrition in periodontal treatment: Antioxidants
(2016)
Nutritional factors are implicated in several systemic diseases and conditions, including overweight and obesity, hypertension, dyslipidemia, type 2 diabetes, cardiovascular disease, osteoporosis that are associated with ...
Advances of Molecular Targeted Therapy in Gastric Cancer
(2016)
Background: Gastric cancer is the second most common cause of cancer-related death in the world, and its prognosis remains poor with a median overall survival of 12 months for advanced disease. Advances in the understanding ...
Evaluation of flame retardant belt usage for underground metal mining [Alev yürütmez bant kullaniminin yeralti metal madencili?i için de?erlendirilmesi]
(2016)
Today, many underground mines are realizing all or a certain portion of the ore transportation by belt conveyor systems. In this study, the requirement to deploy flame-retardant conveyor belts in the case of operating belt ...