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Strong association between lung cancer and the AXIN2 polymorphism
(SPANDIDOS PUBL LTD, 2009)
Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes to carcinogenesis. The effect of the AXIN2 ...
Microsomal epoxide hydrolase polymorphisms
(SPANDIDOS PUBL LTD, 2010)
Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change ...
AXIN2 polymorphism and its association with astrocytoma in a Turkish population
(SPANDIDOS PUBL LTD, 2010)
The product of AXIN2, a component of Writ signalling, plays a role in tumorigenesis and is dysregulated in cancer cells. In order to determine whether the AXIN2 polymorphism is a risk factor for astrocytoma, we analysed ...