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Strong association between lung cancer and the AXIN2 polymorphism
(SPANDIDOS PUBL LTD, 2009)
Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes to carcinogenesis. The effect of the AXIN2 ...
Myeloperoxidase G-463A polymorphism and risk of lung and prostate cancer in a Turkish population
(SPANDIDOS PUBL LTD, 2011)
Myeloperoxidase (M PO) is a phase I enzyme that can bioactivate many specific procarcinogens, including polycyclic aromatic hydrocarbons and aromatic amines. The MPO gene contains a common single nucleotide polymorphism, ...
Microsomal epoxide hydrolase polymorphisms
(SPANDIDOS PUBL LTD, 2010)
Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change ...
Role of SOD2 Ala16Val polymorphism in primary brain tumors
(SPANDIDOS PUBL LTD, 2019)
The present study aimed to investigate the possible association between the genetic polymorphism of the enzyme superoxide dismutase 2 (SOD2, also known as manganese-dependent SOD), Ala16Val (rs4880), and primary brain tumor ...