JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Makale Koleksiyonu by Author "Istanbullu, H., Department of Pharmaceutical Chemistry, EgeUniversity, Izmir, 35100, Turkey -- Zencir, S., Department of Medical Biology, Pamukkale University, Denizli, 20070, Turkey -- Berenyi, A., Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, H-6270, Hungary -- Canturk Kilickaya, P., Department of Pharmaceutical Biotechnology, Cumhuriyet University, Sivas, 58140, Turkey -- Zupko, I., Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, H-6270, Hungary -- Erciyas, E., Department of Pharmaceutical Chemistry, EgeUniversity, Izmir, 35100, Turkey -- Topcu, Z., Department of Pharmaceutical Biotechnology, Ege University, Izmir, 35100, Turkey"
Majority of anti-cancer drugs were shown to exert their activities by interfering with DNA topoisomerase reactions. Since the identification of Camptothecin as the topoisomerase I targeting compound, these enzymes are ...