Browsing Makale Koleksiyonu by Publisher "SPANDIDOS PUBL LTD"
Now showing items 1-12 of 12
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Association between MMP-3 and MMP-9 polymorphisms and coronary artery disease
(SPANDIDOS PUBL LTD, 2016)Matrix metalloproteinase (MMP)-3 and MMP-9 polymorphisms are characterized by plaque stability in coronary arteries. The aim of the current study was to investigate the 5A/6A polymorphism in the MMP-3 gene and C/T polymorphism ... -
AXIN2 polymorphism and its association with astrocytoma in a Turkish population
(SPANDIDOS PUBL LTD, 2010)The product of AXIN2, a component of Writ signalling, plays a role in tumorigenesis and is dysregulated in cancer cells. In order to determine whether the AXIN2 polymorphism is a risk factor for astrocytoma, we analysed ... -
Effects of Ankaferd BloodStopper on bone healing in an ovariectomized osteoporotic rat model
(SPANDIDOS PUBL LTD, 2017)Bone defects resulting from oncological surgical resections, congenital facial anomalies, trauma or infection represent a significant and common clinical problem. The present study aimed to evaluate the effects of a ... -
Effects of MPO-463G/A and -129G/A polymorphisms on coronary artery disease risk and patient survival in a Turkish population
(SPANDIDOS PUBL LTD, 2017)Myeloperoxidase (MPO) is an oxidative hemoprotein compound expressed in polymorphonuclear leukocytes that contributes to inflammatory responses. Coronary artery disease (CAD), as the most prevalent form of heart disease, ... -
Investigation of the association between the MDM2 T309G polymorphism and gastric cancer
(SPANDIDOS PUBL LTD, 2017)Murine double minute clone 2 oncoprotein (MDM2) is a key component in the regulation of the tumour suppressor p53. The association between the MDM2 polymorphism and gastric cancer (GC) has been investigated in Turkish ... -
Investigation of wound healing in rat lung tissues in the postpartum period
(SPANDIDOS PUBL LTD, 2012)To assess the wound healing capabilities of damaged lung tissue in the postpartum period, we investigated the parameters related to wound healing in a rat model of lung damage. Rats were divided into six groups: IA, I B, ... -
Management of neuroendocrine carcinomas of the breast: A rare entity
(SPANDIDOS PUBL LTD, 2011)Neuroendocrine (NE) carcinoma of the breast is extremely rare and constitutes less than 0.1% of all breast tumors. Only a few studies are currently available in the literature and a standard approach to treating this tumor ... -
Microsomal epoxide hydrolase polymorphisms
(SPANDIDOS PUBL LTD, 2010)Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change ... -
Myeloperoxidase G-463A polymorphism and risk of lung and prostate cancer in a Turkish population
(SPANDIDOS PUBL LTD, 2011)Myeloperoxidase (M PO) is a phase I enzyme that can bioactivate many specific procarcinogens, including polycyclic aromatic hydrocarbons and aromatic amines. The MPO gene contains a common single nucleotide polymorphism, ... -
Role of SOD2 Ala16Val polymorphism in primary brain tumors
(SPANDIDOS PUBL LTD, 2019)The present study aimed to investigate the possible association between the genetic polymorphism of the enzyme superoxide dismutase 2 (SOD2, also known as manganese-dependent SOD), Ala16Val (rs4880), and primary brain tumor ... -
Strong association between lung cancer and the AXIN2 polymorphism
(SPANDIDOS PUBL LTD, 2009)Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes to carcinogenesis. The effect of the AXIN2 ... -
Sulfotransferase 1A1 Arg(213)His polymorphism and prostate cancer risk
(SPANDIDOS PUBL LTD, 2011)Sulfotransferase 1A1 (SULT1A1) is a member of the sulfotransferase family that plays an important role in the biotransformation of numerous carcinogenic and mutagenic compounds through sulfation. A transition, G to A at ...