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Therapeutic Targeting of microRNAs in Cancer: Future Perspectives
(WILEY-BLACKWELL, 2015)
The discovery of microRNAs (miRNAs) and their link with cancer has opened a new era in cancer therapeutics. Approximately, 18-24 nucleotides long, miRNAs can up-regulate or down-regulate gene expression in many cancer types ...
A genetic programming-based QSPR model for predicting solubility parameters of polymers
(ELSEVIER SCIENCE BV, 2015)
In this study, linear and nonlinear quantitative structure-property relationship (QSPR) models, respectively called the multiple linear regression based QSPR (MLR-QSPR) model and the genetic programming based QSPR (GP-QSPR) ...
The impact of immunohistochemical staining with ezrin-carbonic anhydrase IX and neuropilin-2 on prognosis in patients with metastatic renal cell cancer receiving tyrosine kinase inhibitors
(SAGE PUBLICATIONS LTD, 2015)
The identification of prognostic factors in patients with renal cell carcinoma (RCC) represents an area of increasing interest. In this retrospective study, we evaluated the prognostic role of carbonic anhydrase-IX, ezrin, ...
Sexual Dysfunction and Sexual Quality of Life in Women with Diabetes: The Study Based on a Diabetic Center
(SPRINGER, 2015)
This study was conducted on a cross-sectional basis for the purpose of determining the prevalence of sexual dysfunction (SD) and sexual quality of life in women with diabetes and, showing the correlation of them with some ...
Frontal lobe syndrome developing after head trauma: case report
(CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2015)
Frontal lobe syndrome (FLS) is a clinical picture caused by damages due to reasons like prefrontal cortex cerebrovascular disease, tumor, infection or head trauma and displaying itself through distinct and permanent ...
Cancer antigen-125 levels predict long-term mortality in chronic obstructive pulmonary disease
(INFORMA HEALTHCARE, 2015)
Background: Cancer antigen-125 (CA-125) might be a useful biomarker to predict long-term mortality in patients with recent exacerbation of chronic obstructive pulmonary disease (COPD). Methods: A total of 87 consecutive ...
Simulating urban growth driven by transportation networks: A case study of the Istanbul third bridge
(ELSEVIER SCI LTD, 2015)
Increasing populations and the related transport volumes are problematic for metropolitan regions in Istanbul especially due to the separation of the city by the Bosphorus strait, which creates significant congestion, ...
Long-term assessment of bone formation in response to Gen Os and Gel 40 xenografts in an experimental rat model
(ALLIED ACAD, 2015)
The study's aim was to assess long-term bone healing associated with two different xenografts in an experimental model of parietal bone defects in rats. We surgically created two symmetrical, full-thickness, parietal bone ...
Neural tube defect family with recessive trait linked to chromosome 9q21.12-21.31
(SPRINGER, 2015)
Meningomyelocele is one of the most common and socioeconomically, psychologically, and physically debilitating neurodevelopmental diseases. A few chromosomal locus and genes have been identified as responsible for the ...
Spectroscopic investigation, FMOs and NLO analyses of Zn(II) and Ni(II) phenanthroline complexes: A DFT approach
(PERGAMON-ELSEVIER SCIENCE LTD, 2015)
Computational studies were carried out on three Zn(II) and three Ni(II) complexes, namely [NiL1(phen)(2)], [ZnL1(phen)(2)], [NiL2(phen)(2)], [ZnL2(phen)(2)], [NiL3(phen)(2)] and [ZnL3(phen)(2)]. These complexes were ...