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Crizotinib-induced toxicity in an experimental rat model
(SPRINGER WIEN, 2016)
The aim of the present study was to evaluate the effect of crizotinib on visceral organs in an experimental rat model. Eighteen Wistar albino rats were divided into three groups: experimental toxicity was induced with ...
The Protective effect of P7C3 against DNA and neuron damage in rat pups with congenital hypothyroidism
(Elsevier Masson SAS, 2018)
Congenital hypothyroidism (CH) is defined as congenital thyroid hormone deficiency. The aim of this study was to examine the DNA and neuron damage in rat pups with CH and to evaluate the beneficial effects of 3.6-Dibromo ...
Possible Role of K-ras Oncogene in Mutagenic Activity of Ethylnitrosourea on Lymphocyte Hyperproliferation in Rat Colon
(2001)
N-ethyl-N-nitrosourea (ENU) is a potential carcinogenic agent that is commonly used in industry. Therefore the present study aimed to find out the possible effects of this agent on the rat digestive tract especially on the ...
Blastocyst Implantation in Rats : A Morphological Approach
(1998)
Very complex cellular events take place at the morphological and molecular levels both in the maternal and embryonic sites during blastocyst implantation. Although the morphological alterations in the gestational stages ...
Investigation of oxidative stress during fracture healing in the rats
(2005)
One of the most damaging effects of reactive oxygen species (ROS) is lipid peroxidation, the end-product of which is malondialdehyde (MDA). This study was aimed to evaluate erythrocyte MDA levels during fracture healing ...
Effects of tamoxifen administration in rat vaginas: An ultrastructural and light microscopy study
(2002)
Background: Tamoxifen (TAM) inhibits the initiation of carcinogen induced rat mammary tumours and is administrered for extended periods after the initiation of carcinogenesis. It is also a widely used treatment for breast ...
Effects of Short-Term Hydrocarbon Inhalation on Rat Tracheal Mucosa
(1998)
Hydrocarbons used as solvents in industry are thought to have effects on respiratory system. However, its effect on tracheal morphology and function is poorly investigated. Therefore the present study attempted to investigate ...
Development of Arteriovenous Anastomoses in Rattus Norvegicus Species during the Fetal Period
(1996)
In this study carried out on the development of arteriovenous anastomoses (AVAs) in Rattus norvegicus species, the fetus was followed up 10 days after post coitum (pc). The sections obtained from the fetuses of 10-20-day ...
Comparison of efficiency of Clexane® "enoxaparin sodium" and methylene blue in prevention of adhesions after cesarean section in pregnant rats [Gebe Ratlarda Sezaryen Operasyonu Sonrasi{dotless}, Adezyonlari{dotless}n Önlenmesinde Clexane® "Enoksapari?n Sodyum" ve Meti?len Mavi?si?'nin Etki?nli?kleri?ni?n Karşi{dotless}laşti{dotless}ri{dotless}lmasi{dotless}]
(2012)
Objective: To compare the effectiveness of fluid barriers, Clexane® "enoxaparin sodium" and methylene blue, in prevention of adhesion formation after cesarean section. We aimed to reduce the secondary infertility caused ...
Possible role of DNA hypomethylation in mutagenic activity of N'-ethyl-N'-nitrosourea (ENU) on subcutaneous rhabdomyosarcoma in rat
(2001)
Purpose: The aim of the study was to find out the possible effects of DNA hypomethylation on N'-ethyl-N'-nitrosourea (ENU) mutagenity. Methods: Rats were injected with 300mg/kg body weight-body weight ENU (i.p.)for 45 weeks ...