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Frequency of the mdr-1 C > T gene polymorphism in patients with COPD
(HOSPITAL CLINICAS, UNIV SAO PAULO, 2010)
BACKGROUND AND AIM: The multi-drug resistant-1 (MDR-1) gene is located on human chromosome 7 and encodes a glycosylated membrane protein that is a member of the ATP-binding cassette transporters superfamily. The aim of the ...
HRCT findings in rats with long-term exposure to smokes of cigarette and biomass fuels
(ACADEMIC JOURNALS, 2010)
The harmful effects of tobacco's smoke have been well-known for years and several studies revealed that exposure to biomass smoke can markedly increase the prevalence of respiratory disorders. In this study, separate and ...
A Frame-Shift Mutation in the SLC34A2 Gene in Three Patients with Pulmonary Alveolar Microlithiasis in an Inbred Family
(JAPAN SOC INTERNAL MEDICINE, 2010)
Pulmonary alveolar microlithiasis (PAM) is a rare disease characterized by the presence of small calculi in the alveolar space. The SLC34A2 is thought to be responsible for the disease. We encountered three siblings of an ...
Effects of long-term non-invasive home mechanical ventilation on chronic respiratory failure
(TAYLOR & FRANCIS LTD, 2010)
Objective: Chronic respiratory failure (CRF) is a syndrome defined by certain disturbances in arterial blood gases. Non-invasive mechanical ventilation (NIMV) is an increasingly used treatment modality in respiratory ...