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Effects of Proton Pump Inhibitors and H-2 Receptor Antagonists on the Ileum Motility
(HINDAWI PUBLISHING CORPORATION, 2011)
Objectives. To investigate the effects of proton pump inhibitors (PPIs) and H-2 receptor antagonists on ileum motility in rats with peritonitis and compare changes with control group rats. Methods. Peritonitis was induced ...
Evaluation of effects of T and N type calcium channel blockers on the electroencephalogram recordings in Wistar Albino Glaxo/Rij rats, an absence epilepsy model
(MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2015)
Objectives: It is suggested that excessive calcium entry into neurons is the main triggering event in the initiation of epileptic discharges. We aimed to investigate the role of T and N type calcium channels in absence ...
Investigation of the vasorelaxant effects of moxonidine and its relaxation mechanism on the human radial artery when used as a coronary bypass graft
(OXFORD UNIV PRESS, 2015)
In both low- and high-risk patients undergoing coronary artery bypass grafting, the internal mammary artery is the first choice of arterial graft, and the second choice is the radial artery (RA). Unfortunately, RA spasms ...
Anticancer Effect of COX-2 Inhibitor DuP-697 Alone and in Combination with Tyrosine Kinase Inhibitor (E7080) on Colon Cancer Cell Lines
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)
Colorectal cancer remains one of the most common types of cancer and a leading cause of cancer death worldwide. In this study, we aimed to investigate effects of DuP-697, an irreversible selective inhibitor of COX-2 on ...
Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats
(TAYLOR & FRANCIS LTD, 2011)
Background. Alpha 2 (alpha(2))-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The purpose of this study was to investigate ...
Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis
(W J G PRESS, 2009)
AIM: To investigate in vitro effects of propofol, midazolam and dexmedetomidine, which are commonly used anaesthesic or sedatives, on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic ...
Investigation of Antitumor Effects of Sorafenib and Lapatinib Alone and in Combination on MCF-7 Breast Cancer Cells
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)
Background: Breast cancer evolution and tumor progression are controlled by complex interactions between steroid receptors and growth factor receptor signaling. Aberrant growth factor receptor signaling can augment or ...
Zimelidine attenuates the development of tolerance to morphine-induced antinociception
(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2012)
Objectives: The aim of this study was to investigate effect of zimelidine (a serotonin reuptake inhibitor) on morphine-induced tolerance in rats. Materials and Methods: Male Wistar albino rats weighing 160-180 g were used ...
Investigation of the Relaxant Effect Mechanism of Ketamine on Normal and Ovalbumin-Induced Trachea in Guinea Pigs
(ORTADOGU AD PRES & PUBL CO, 2011)
Objective: The aim of this study was to investigate of effects and the possible mechanisms of effects of ketamine on the isolated trachea preparations from control and ovalbumin sensitized guinea pigs. Material and Methods: ...
Ineffective Doses of Dexmedetomidine Potentiates the Antinociception Induced by Morphine and Fentanyl in Acute Pain Model
(KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2013)
The aim of this study was to evaluate the synergistic potentiation effect of ineffective doses of dexmedetomidine on antinociception induced by morphine and fentanyl in acute pain model in rats. Seventy albino Wistar rats ...