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Possible Role of K-ras Oncogene in Mutagenic Activity of Ethylnitrosourea on Lymphocyte Hyperproliferation in Rat Colon
(2001)
N-ethyl-N-nitrosourea (ENU) is a potential carcinogenic agent that is commonly used in industry. Therefore the present study aimed to find out the possible effects of this agent on the rat digestive tract especially on the ...
Investigation of oxidative stress during fracture healing in the rats
(2005)
One of the most damaging effects of reactive oxygen species (ROS) is lipid peroxidation, the end-product of which is malondialdehyde (MDA). This study was aimed to evaluate erythrocyte MDA levels during fracture healing ...
Effects of tamoxifen administration in rat vaginas: An ultrastructural and light microscopy study
(2002)
Background: Tamoxifen (TAM) inhibits the initiation of carcinogen induced rat mammary tumours and is administrered for extended periods after the initiation of carcinogenesis. It is also a widely used treatment for breast ...
Possible role of DNA hypomethylation in mutagenic activity of N'-ethyl-N'-nitrosourea (ENU) on subcutaneous rhabdomyosarcoma in rat
(2001)
Purpose: The aim of the study was to find out the possible effects of DNA hypomethylation on N'-ethyl-N'-nitrosourea (ENU) mutagenity. Methods: Rats were injected with 300mg/kg body weight-body weight ENU (i.p.)for 45 weeks ...
Development of arteriovenous anastomoses in the skins of rats during the fetal period
(2003)
In order to describe the development of AVAs in Rattus norvegicus species, the fetus were followed up for 10 days after coitum. The serial sections obtained from the fetuses of 10-20-day rats were subjected for examination ...
Epidermal Growth Factor Receptor (EGFR) Immunolocalization in the Male Rat Reproductive Tract during Pre-and Postnatal Periods
(2000)
A number of recent studies suggest the effects of several growth factors as well as genetic factors on the development and differentiation of the testes and excretory ducts. One of the most important growth factors affecting ...