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Strong association between lung cancer and the AXIN2 polymorphism
(SPANDIDOS PUBL LTD, 2009)
Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes to carcinogenesis. The effect of the AXIN2 ...
Sulfotransferase 1A1 Arg(213)His polymorphism and prostate cancer risk
(SPANDIDOS PUBL LTD, 2011)
Sulfotransferase 1A1 (SULT1A1) is a member of the sulfotransferase family that plays an important role in the biotransformation of numerous carcinogenic and mutagenic compounds through sulfation. A transition, G to A at ...
Myeloperoxidase G-463A polymorphism and risk of lung and prostate cancer in a Turkish population
(SPANDIDOS PUBL LTD, 2011)
Myeloperoxidase (M PO) is a phase I enzyme that can bioactivate many specific procarcinogens, including polycyclic aromatic hydrocarbons and aromatic amines. The MPO gene contains a common single nucleotide polymorphism, ...
Role of SOD2 Ala16Val polymorphism in primary brain tumors
(SPANDIDOS PUBL LTD, 2019)
The present study aimed to investigate the possible association between the genetic polymorphism of the enzyme superoxide dismutase 2 (SOD2, also known as manganese-dependent SOD), Ala16Val (rs4880), and primary brain tumor ...
Investigation of the association between the MDM2 T309G polymorphism and gastric cancer
(SPANDIDOS PUBL LTD, 2017)
Murine double minute clone 2 oncoprotein (MDM2) is a key component in the regulation of the tumour suppressor p53. The association between the MDM2 polymorphism and gastric cancer (GC) has been investigated in Turkish ...