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Now showing items 11-17 of 17
Zimelidine attenuates the development of tolerance to morphine-induced antinociception
(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2012)
Objectives: The aim of this study was to investigate effect of zimelidine (a serotonin reuptake inhibitor) on morphine-induced tolerance in rats. Materials and Methods: Male Wistar albino rats weighing 160-180 g were used ...
Role of new agents affecting NO/cGMP pathway on ovalbumin-sensitized guinea pig trachea
(INFORMA HEALTHCARE, 2012)
Asthma is a chronic inflammatory disease in which cell components play important roles. We aimed to evaluate the effects of NO/cGMP cleavage at trachea preparations isolated from ovalbumin-sensitized guinea pigs in vitro. ...
Evaluation of urinary bladder function after acute spinal cord injury: an experimental study
(TURKISH JOINT DISEASES FOUNDATION, 2010)
Objectives: The aim of this study was to evaluate the efficacy of early surgical decompression of acute spinal cord injury through the evaluation of urinary bladder function in rabbits. Materials and methods: The study was ...
The nitric oxide-cGMP signaling pathway plays a significant role in tolerance to the analgesic effect of morphine
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2011)
Although the phenomenon of opioid tolerance has been widely investigated, neither opioid nor nonopioid mechanisms are completely understood. The aim of the present study was to investigate the role of the nitric oxide ...
Investigation of Relaxant Effects of New Agents Affecting Nitric Oxide/Cyclic Guanosine Monophosphate Pathway on Sheep Oddi Sphincter
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Objectives: Nitric oxide (NO) is a potent nonadrenergic, noncholinergic mediator of gastrointestinal smooth muscle. We aimed to investigate the effects of new NO/cyclic guanosine monophosphate (cGMP) pathway-affecting ...
Attenuation of morphine antinociceptive tolerance by cannabinoid CB1 and CB2 receptor antagonists
(SPRINGER JAPAN KK, 2015)
Cannabinoid CB1 and CB2 receptor antagonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The aim of this study was to investigate the ...
Investigation of the relaxant effects of pancuronium, rocuronium, vecuronium and mivacurium on rat thoracic aorta
(LIPPINCOTT WILLIAMS & WILKINS, 2009)
Background and objective Pancuronium, vecuronium, mivacurium and rocuronium are nondepolarizing neuromuscular blocking agents, which are competitive antagonists against acetylcholine at nicotinic receptors, and considered ...