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Now showing items 11-16 of 16
Effects of the Chemokine Receptor 5 (CCR5)-Delta32 Mutation on Hepatitis C Virus-Specific Immune Responses and Liver Tissue Pathology in HCV Infected Patients
(KOWSAR PUBL, 2014)
Background: The specific antiviral T cells provide CC chemokine receptor 5 (CCR5) for the immune response during the hepatitis C virus (HCV) infection. Heterogenous and/or homozygous 32 base pair deletion in CCR5 gene (CCR5 ...
CCR2 Polymorphism in Chronic Renal Failure Patients Requiring Long-Term Hemodialysis
(JAPAN SOC INTERNAL MEDICINE, 2011)
Objective A number of chemokines and chemokine receptors are produced by intrinsic renal cells as well as by infiltrating cells during renal inflammation. The CCR2 chemokine receptor mediates leukocyte chemoattraction in ...
A Frame-Shift Mutation in the SLC34A2 Gene in Three Patients with Pulmonary Alveolar Microlithiasis in an Inbred Family
(JAPAN SOC INTERNAL MEDICINE, 2010)
Pulmonary alveolar microlithiasis (PAM) is a rare disease characterized by the presence of small calculi in the alveolar space. The SLC34A2 is thought to be responsible for the disease. We encountered three siblings of an ...
Heterozygous Deletion of Exon 8 in WFS1 Gene in Two Wolfram Syndrome Probands with Hearing Loss: Case Report
(ORTADOGU AD PRES & PUBL CO, 2011)
Point mutations in the Wolfram syndrome 1 gene (WFS1) are attributed the autosomal dominant and/or recessive mild type sensorineural hearing loss in first degree relatives. Total genomic DNA was isolated from peripheral ...
Association between ABCB1 (MDR1) Gene 3435 C > T Polymorphism and Colchicine Unresponsiveness of FMF Patients
(TAYLOR & FRANCIS LTD, 2011)
The multidrug resistance gene-1 (MDR1, adenosine triphosphate-binding cassette transporter: ABCB1, P-glycoprotein) encodes membrane proteins that play a crucial role in protecting cells from xenobiotics, chemicals, and ...
Micronucleus frequencies in groups receiving external or internal radiation
(MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2016)
Objective: In the current study, we aimed to explore whether there is alteration between pre-and post-treatment micronucleus (MN) frequencies induced by internal and external ionizing radiation. Materials and Methods: The ...