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Now showing items 11-20 of 20
Studying the Association between Sudden Hearing Loss and DNA N-Methyltransferase 1 (DNMT1) Genetic Polymorphism
(AVES, 2017)
OBJECTIVE: The aim of the present study was to investigate whether there was any relationship between some DNA N-methyltransferase 1 (DNMT1) polymorphisms and susceptibility to idiopathic sudden sensorineural hearing loss ...
Effect of tumour necrosis factor-alpha and interleukin-6 promoter polymorphisms on course of Crimean-Congo hemorrhagic fever in Turkish patients
(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015)
Objective: In this case-control study, we investigated whether IL-6 (-174G/C) and TNF-alpha (-308G/A) gene polymorphisms affect the clinical course and outcome of CCHF. Methods: Total 150 patients with CCHF and 170 controls ...
Microsomal epoxide hydrolase polymorphisms
(SPANDIDOS PUBL LTD, 2010)
Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change ...
Multiple Inherited Thrombophilic Gene Polymorphisms in Spontaneous Abortions in Turkish Population
(CELLULAR & MOLECULAR BIOLOGY RESEARCH CENTER, 2015)
The aim of this study was to investigate the possible role of multiple inherited thrombophilic gene variations in women with unexplained spontaneous abortions. For this purpose, the Factor V Leiden (FVL) (rs6025), Prothrombin ...
Glutathione-S-Transferase Variants are not Associated With Increased Carotid Intima-Media Thickness in Turkish Familial Mediterranean Fever Patients
(TURKISH LEAGUE AGAINST RHEUMATISM, 2016)
Objectives: This study aims to evaluate the carotid intima-media thickness (CIMT) in patients diagnosed with familial Mediterranean fever (FMF) and investigate whether there is a relationship between glutathione-S-transferase ...
Role of SOD2 Ala16Val polymorphism in primary brain tumors
(SPANDIDOS PUBL LTD, 2019)
The present study aimed to investigate the possible association between the genetic polymorphism of the enzyme superoxide dismutase 2 (SOD2, also known as manganese-dependent SOD), Ala16Val (rs4880), and primary brain tumor ...
AXIN2 polymorphism and its association with astrocytoma in a Turkish population
(SPANDIDOS PUBL LTD, 2010)
The product of AXIN2, a component of Writ signalling, plays a role in tumorigenesis and is dysregulated in cancer cells. In order to determine whether the AXIN2 polymorphism is a risk factor for astrocytoma, we analysed ...
MBL, P2X7, and SLC11A1 gene polymorphisms in patients with oropharyngeal tularemia
(TAYLOR & FRANCIS LTD, 2016)
Conclusion: A significant association was found of oropharyngeal tularemia with SLC11A1 allele polymorphism (INT4G/C) and MBL2 C+4T (P/Q). These results indicate C allele and Q allele might be a risk factor for the development ...
Significant Association Between Polymorphisms of Wnt Antagonist Genes and Lung Cancer
(BMJ PUBLISHING GROUP, 2015)
Further elucidation of the molecular mechanisms underlying lung cancer (LC) is essential for the development of new effective therapeutic agents. Recently, involvement of Wnt antagonists in oncogenesis has been demonstrated ...
Investigation of the association between the MDM2 T309G polymorphism and gastric cancer
(SPANDIDOS PUBL LTD, 2017)
Murine double minute clone 2 oncoprotein (MDM2) is a key component in the regulation of the tumour suppressor p53. The association between the MDM2 polymorphism and gastric cancer (GC) has been investigated in Turkish ...