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Effect of magnesium sulfate, isradipine, and ritodrine on contractions of myometrium: pregnant human and rat
(BLACKWELL MUNKSGAARD, 2002)
Background. Magnesium sulfate, isradipine, and ritodrine are smooth muscle relaxants used for treating preterm labor. The aim of this study is to investigate the action profile of these drugs on the amplitude and frequency ...
Chloride channel blockers 5-nitro-2-(3-phenylpropylamino) benzoic acid and anthracene-9-carboxylic acid inhibit contractions of pregnant rat myometrium in vitro
(ELSEVIER SCIENCE INC, 2001)
OBJECTIVE: We compared in vitro relaxant effect of chloride channel modulators, such as 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) and anthracene-9-carboxylate (9-AC), and beta (2)-adrenergic agonists, such as ...
Inhibitor effect of omeprazole in isolated human myometrial smooth muscle
(PERGAMON-ELSEVIER SCIENCE LTD, 2001)
The aim of the present study was to investigate the effect of omeprazole, an H+-K+-ATPase inhibitor, in myometrial smooth muscle strips from women undergoing elective caesarean section at term. Isolated myometrial strips ...
Comparison of the effects of nimesulide and 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanone (DFU) on contractions of isolated pregnant human myometrium
(ELSEVIER SCIENCE BV, 2004)
Objective: To compare the effects of 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanone (DFU) and nimesulide, selective COX-2 inhibitors, on the amplitude and frequency of KCI-, oxytocin-, and ...
Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium
(ELSEVIER SCIENCE BV, 2005)
This study was designed to compare the effects of YCA (3-(5-hydroxymethyl-2'-furyl)-1-benzyl indazole), a nitric oxide (NO)independent soluble guanylate cyclase activator, and diethylenetriamine-NONOate (DETA/NO), a NO ...
Comparison of effects of formoterol and BRL 37344 on isolated term-pregnant rat myometrial strips in vitro
(ELSEVIER SCIENCE BV, 2006)
This study was designed to compare the effects of beta-adrenoccptoy agonists formoterol and BRL 37344 on spontaneous contractions and the levels of cAMP and cGMP of myometrial strips isolated from timed-pregnant rats. ...
Effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid, anthracene-9-carboxylate, and zaprinast on endothelin-1-induced contractions of pregnant rat myometrium
(ELSEVIER SCI IRELAND LTD, 2002)
Objective: The effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB), anthracene-9-carboxylate (9-AC) (chloride channel blockers) and zaprinast (an inhibitor of phosphodiesterase-5) on endothelin-1 (ET-1) induced ...
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits the spontaneous contractions of isolated pregnant rat myometrium
(JAPANESE PHARMACOLOGICAL SOC, 2004)
The aim of this study was to investigate the effect of YC-1 (3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole) on spontaneous contractions and levels of cyclic GMP (cGMP) of myometrial strips isolated from pregnant rats. ...
Comparison of effects of cyclooxygenase inhibitors on myometrial contraction and constriction of ductus arteriosus in rats
(ELSEVIER SCIENCE BV, 2004)
The aim of this study was to compare the tocolytic effect of a selective cylooxygenase-2 inhibitor, DFU (5,5-dimethyl-3(3-fluorophenyl)4-(4-methylsulphonyl)phenyl-2(5H)-furanone), indomethacin and nimesulide on myometrial ...
Prevention of postoperative adhesion formation in rat uterine horn model by nimesulide: a selective COX-2 inhibitor
(OXFORD UNIV PRESS, 2001)
BACKGROUND: Pelvic surgery is one of the main causes of intraperitoneal (i.p.) adhesions that create various medical problems including pelvic pain, bowel obstructions and female infertility. A rat model was used to ...