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Everolimus as an mTOR Inhibitor Suppresses Endometriotic Implants: an Experimental Rat Study
(GEORG THIEME VERLAG KG, 2017)
Introduction Mammalian target of rapamycin is a pathway to block apoptosis. Recent studies showed that the activity of mammalian target of rapamycin pathway increases in endometriotic lesions. Aim of the present study was ...
Renal Cell Apoptosis and New Treatment Options in Sepsis-Induced Acute Kidney Injury
(INFORMA HEALTHCARE, 2013)
Sepsis is a common and important cause of mortality in critically ill patients. Acute kidney injury (AKI) is one of the most important factors determining morbidity and mortality in the prognosis of sepsis. Recent studies ...
Synthesis and biological evaluation of novel indenopyrazole derivatives
(WILEY, 2019)
A series of novel indenopyrazole derivatives 2a-j and 3a-j were synthesized from the reaction of 1-(4-(hydroxy(1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl)phenyl)-3-phenylurea derivatives 1a-j with hydrazine and phenylhydrazine, ...
Melatonin and tadalafil treatment improves erectile dysfunction after spinal cord injury in rats
(WILEY, 2014)
Oxidative stress plays an important role both in spinal cord injury (SCI) and erectile dysfunction (ED). The present study investigated the effects of melatonin and tadalafil treatment alone or in combination on SCI-induced ...
Apoptosis and its relation with clinical course in patients with Crimean-Congo hemorrhagic fever
(WILEY, 2019)
Crimean-Congo hemorrhagic fever (CCHF) is a tick-mediated viral infection. Patients with CCHF may show various clinical presentations. The cause of this difference in the clinical course is not completely understood. ...
Evaluation of the Cytotoxic effects of various monomers In vitro also their effects on Apoptosis and GFAP immunolocalization in rat spinal cord In vivo
(DRUNPP-SARAJEVO, 2011)
Biomaterials are mostly polymers made by monomers, and are used in artificial organ production in contemporary medicine. They are prepared by the polimerization reaction of certain monomers. The aim of the present study ...
Tumor necrosis factor-alpha induced caspase-3 activation-related iNOS gene expression in ADP-activated platelets
(TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2017)
Platelets are sensitive cells and are easily activated by different stimulants in the circulation system. It is known that tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine and plays a role in inflammation. ...
The neuroprotective effects of 2-APB in rats with experimentally-induced severe acute pancreatitis
(COMENIUS UNIV, 2018)
AIM: The objective of this study was to determine the neuroprotective effects of 2-aminoethyl diphenyl-borinate (2-APB) on the brains of rats with experimentally-induced severe acute pancreatitis. MATERIALS AND METHODS: ...
Synthesis of Diflunisal Thiazolidinones as Anticancer Agents
(BENTHAM SCIENCE PUBL LTD, 2016)
A series of diflunisal 4-thiazolidinones were synthesized. Some selected compounds were determined at one dose towards the full panel of 60 human cancer cell lines by National Cancer Institute. 2',4'-Difluoro-4-hydroxy-N ...
Rho GTPases control postnatal apoptosis and neuronal density in the cerebral cortex
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
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