Torsades de pointes with a severely prolonged QT interval induced by an initial low dose sotalol intake
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Many drugs, including sotalol, have been implicated in prolonging QT interval and triggering torsades de pointes, a potentially fatal ventricular arrhythmia, especially during chronic therapy or in case of acute high dose toxicity. We report here a case with a severely prolonged QT interval and torsades de pointes after an initial intake of low dose sotalol (80 mg), indicating a probable inherent individual oversensitivity to sotalol. © 2006 Elsevier Ireland Ltd. All rights reserved.