| dc.description.abstract | The present work examined the in vitro antimicrobial and antioxidant activities of the essential oil and methanol extract from Achillea biebersteinii Afan. (Asteraceae). The essential oil exhibited antimicrobial activity against 8 bacteria, 14 fungi and the yeast C. albicans, whereas methanolic extract remained inactive. The antioxidative capacity of the samples was evaluated by using DPPH (2,2-diphenyl-1-picrylhydrazyl) and ?-carotene/linoleic acid assays. In both assays, the extract showed better antioxidative capacity than the oil. The extract reduced the stable free radical DPPH with lower IC 50 value (89.90 ?g/ml) than the oil (8900 ?g/ml). In the ?-carotene/linoleic acid assay, the samples were not effectively able to inhibit the linoleic acid oxidation, exhibiting only 22.7% (the extract) and 16% (the essential oil) inhibitions at 2 mg/ml, far below than that of BHT (97.0%). Total phenolic constituent of the extract was 51 ?g/mg (5.1%, w/w) as gallic acid equivalent. GC-MS analysis of the essential oil resulted in the identification of 64 components representing 92.24% of the oil. Piperitone, camphor and 1,8-cineole (eucalyptol) were the main constituents. © TÜBİTAK. | en_US |
| dc.contributor.department | Bariş, Ö., Department of Biology, Faculty of Arts and Science, Atatürk University, 25240 Erzurum, Turkey -- Güllüce, M., Department of Biology, Faculty of Arts and Science, Atatürk University, 25240 Erzurum, Turkey -- Şahin, F., Department of Genetic and Bioengineering, Faculty of Engineering and Architecture, Kayisdagi, Yeditepe University, 34755 Istanbul, Turkey -- Özer, H., Department of Crop Science, Faculty of Agriculture, Atatürk University, 25240 Erzurum, Turkey -- Kiliç, H., Department of Chemistry, Faculty of Art and Science, Atatürk University, 25240 Erzurum, Turkey -- Özkan, H., Ministry of Health of Turkey, Erzurum Regional Hygiene Institute, 25240 Erzurum, Turkey -- Sökmen, M., Department of Chemistry, Faculty of Arts and Science, Cumhuriyet University, 58140 Sivas, Turkey -- Özbek, T., Department of Biology, Institute of Natural and Applied Sciences, Atatürk University, 25240 Erzurum, Turkey | en_US |
