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dc.contributor.authorYildirim A.
dc.contributor.authorOzdemir O.
dc.contributor.authorGül E.
dc.contributor.authorYildirim B.
dc.contributor.authorElagöz S.
dc.contributor.authorKunt T.
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:12:36Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:12:36Z
dc.date.issued2006
dc.identifier.issn1300-7475
dc.identifier.urihttps://hdl.handle.net/20.500.12418/4409
dc.description.abstractOBJECTIVES: Nuclear characteristics of epithelial cells in nasal polyps were analyzed. PATIENTS AND METHODS: The slides of 35 patients who underwent surgery for nasal polyposis and 18 slides of normal mucosa were examined. The specimens were stained with hematoxylin-eosin. Tissue sections were analyzed by a CCD camera and the Karyotype Program of Human Cytogenetics Nomenclature System on a Macintosh computer (OS 9). Fifty epithelial cells in each slide were randomly selected and transferred to the automated karyotyping system and photographed. The diameters of the nuclei were measured and some peculiar nuclear features were examined, including unsmooth appearance of the nuclear membrane, anaphase-bridge, and binucleation. RESULTS: There were significant differences between nasal polyp and normal mucosa groups in terms of nuclear diameter, perimeter, and volume, with all variables being greater in the nasal polyp group (p=0.001). Unusual nuclear features differed significantly (unsmooth nuclear membrane appearance, p<0.001; anaphase-bridge, p=0.041; binucleation, p=0.018), as well. CONCLUSION: Epithelial cells of nasal polyps exhibit nuclear instability.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleKaryometric analysis of nasal polyps.en_US
dc.typearticleen_US
dc.relation.journalKulak burun bo?az ihtisas dergisi : KBB = Journal of ear, nose, and throaten_US
dc.contributor.departmentYildirim, A., Department of Otolaryngology, Medicine Faculty of Cumhuriyet University, Sivas, Turkey -- Ozdemir, O., Department of Otolaryngology, Medicine Faculty of Cumhuriyet University, Sivas, Turkey -- Gül, E., Department of Otolaryngology, Medicine Faculty of Cumhuriyet University, Sivas, Turkey -- Yildirim, B., Department of Otolaryngology, Medicine Faculty of Cumhuriyet University, Sivas, Turkey -- Elagöz, S., Department of Otolaryngology, Medicine Faculty of Cumhuriyet University, Sivas, Turkey -- Kunt, T., Department of Otolaryngology, Medicine Faculty of Cumhuriyet University, Sivas, Turkeyen_US
dc.identifier.volume16en_US
dc.identifier.issue6en_US
dc.identifier.endpage254en_US
dc.identifier.startpage251en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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