Investigation of oxidative stress during fracture healing in the rats
dc.contributor.author | Yeler H. | |
dc.contributor.author | Tahtabas F. | |
dc.contributor.author | Candan F. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:12:43Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:12:43Z | |
dc.date.issued | 2005 | |
dc.identifier.issn | 0263-6484 | |
dc.identifier.uri | https://dx.doi.org/10.1002/cbf.1199 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/4458 | |
dc.description.abstract | One of the most damaging effects of reactive oxygen species (ROS) is lipid peroxidation, the end-product of which is malondialdehyde (MDA). This study was aimed to evaluate erythrocyte MDA levels during fracture healing in rats. Thirty male rats were used and the rats were divided into two groups to serve as controls and tests. Six rats were used as a control group that was not subject to fracture. The remaining 24 rats were divided into four groups and erythrocyte MDA levels were examined on days 5, 10, 20 and 30 post fracture. The right fibulas of rats were broken by manual angulation in the experimental group. The erythrocyte malondialdehyde level was measured in the experimental and control groups. The difference between malondialdehyde levels of control and experimental groups was statistically significant (p < 0.05). Oxidative stress clearly increases during fracture healing in rats. Copyright © 2005 John Wiley & Sons, Ltd. | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.1002/cbf.1199 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Fracture healing | en_US |
dc.subject | Free oxygen radicals | en_US |
dc.subject | Malondialdehyde | en_US |
dc.subject | Oxidative stress | en_US |
dc.subject | Rat | en_US |
dc.title | Investigation of oxidative stress during fracture healing in the rats | en_US |
dc.type | article | en_US |
dc.relation.journal | Cell Biochemistry and Function | en_US |
dc.contributor.department | Yeler, H., Dept. Oral and Maxillofacial Surg., Faculty of Dentistry, University of Cumhuriyet, 58140, Sivas, Turkey -- Tahtabas, F., Dept. Oral and Maxillofacial Surg., Faculty of Dentistry, University of Cumhuriyet, 58140, Sivas, Turkey -- Candan, F., Department of Chemistry, Faculty of Science and Literature, Cumhuriyet University, 58140, Sivas, Turkey | en_US |
dc.identifier.volume | 23 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 139 | en_US |
dc.identifier.startpage | 137 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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