dc.contributor.author | Gonlugur U. | |
dc.contributor.author | Bakici M.Z. | |
dc.contributor.author | Ozdemir L. | |
dc.contributor.author | Akkurt I. | |
dc.contributor.author | Icagasioglu S. | |
dc.contributor.author | Gultekin F. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:12:56Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:12:56Z | |
dc.date.issued | 2003 | |
dc.identifier.issn | 1476-0711 | |
dc.identifier.uri | https://dx.doi.org/10.1186/1476-0711-2-5 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/4549 | |
dc.description.abstract | Background: Lower respiratory tract infections due to Pseudomonas aeruginosa have a high mortality rate. Antibacterial activity of various antibiotics against P. aeruginosa isolated from each hospital depends on the variety or amount of antibiotics used in each hospital. Method: A total of 249 respiratory isolates of Pseudomonas aeruginosa in Sivas (Turkey) were included between January-1999 and January-2002. Isolates were tested against 14 different antibiotics by a disc diffusion method or standardized microdilution technique. Results: Organisms were cultured from the following specimens: sputum (31.3%), transtracheal/endotracheal aspirates (37.8%), and bronchial lavage (30.9%). Isolates in bronchial lavage were highly susceptible to cefoperazone and aminoglycosides. Resistance to ampicillin/sulbactam was 98.8%, ticarcillin 40.1%, ticarcillin/clavulanic acid 11.2%, piperacillin 21.8%, aztreonam 66.6%, cefotaxim 75.4%, ceftriaxone 84.2%, cefoperazone 39.0%, ceftazidime 50.8%, gentamicin 57.5%, tobramycin 58.4%, amikacin 25.4%, ciprofloxacin 16.1%, and imipenem/cilastatin 21.6%. The term multidrug-resistant P. aeruginosa covered resistance to imipenem, ciprofloxacin, ceftazidime, gentamicin, and piperacillin. 1.2% of isolates were multidrug-resistant. Conclusions: These findings suggest that amikacin resistance increases progressively in Turkey. Piperacillin and ticarcillin/clavulanate were the most active agents against both imipenem- and ciprofloxacin-resistant isolates in our region. © 2003 Gonlugur et al;licensee BioMed Central Ltd. | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.1186/1476-0711-2-5 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | Retrospective analysis of antibiotic susceptibility patterns of respiratory isolates of Pseudomonas aeruginosa in a Turkish University Hospital | en_US |
dc.type | article | en_US |
dc.relation.journal | Annals of Clinical Microbiology and Antimicrobials | en_US |
dc.contributor.department | Gonlugur, U., Department of Chest Diseases, Cumhuriyet University Medical School, Sivas, Turkey -- Bakici, M.Z., Department of Microbiology, Cumhuriyet University Medical School, Sivas, Turkey -- Ozdemir, L., Department of Public Health, Cumhuriyet University Medical School, Sivas, Turkey -- Akkurt, I., Department of Chest Diseases, Cumhuriyet University Medical School, Sivas, Turkey -- Icagasioglu, S., Department of Internal Medicine, Cumhuriyet University Medical School, Sivas, Turkey -- Gultekin, F., Department of Internal Medicine, Cumhuriyet University Medical School, Sivas, Turkey | en_US |
dc.identifier.volume | 2 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |