dc.contributor.author | Mutlu A.E. | |
dc.contributor.author | Boztosun A. | |
dc.contributor.author | Sümer D. | |
dc.contributor.author | Yanik A. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:14:16Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:14:16Z | |
dc.date.issued | 2012 | |
dc.identifier.issn | 1307699X | |
dc.identifier.uri | https://dx.doi.org/10.5505/tjod.2012.53254 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/4894 | |
dc.description.abstract | Objective: To compare the effectiveness of fluid barriers, Clexane® "enoxaparin sodium" and methylene blue, in prevention of adhesion formation after cesarean section. We aimed to reduce the secondary infertility caused by adhesions after the operation Design: Pregnancy was terminated on the day 21 of gestation by cesarean section via bilateral uterine incision in 24 inbred, pregnant Wistar-Albino rats. The rats were divided into three groups. Interventions: The first group underwent standard surgery, where intra-peritoneal saline was given before abdominal closure. In the second group, methylene blue was sprayed on the defect at the anterior uterine horn after cesarean operation, whereas Clexane ® "Low-Molecular-Weight Heparin" (LMWH) was sprayed in the third group. After 3 weeks, all rats were sacrificed in order to determine the adhesion scores. Macroscopic and microscopic adhesion scores were statistically analyzed among groups. Main outcome measures: No significant difference was detected between methylene blue group and control group in terms of adhesion scores (p>0.05). It was found that adhesion scores in the LMWH group was significantly higher than the control group, suggesting that adhesions was increased by the administration of LMWH (p<0.05). Conclusion: According to results of our study, direct application of liquid adhesion barriers to injured surface seems to be partially ineffective in the prevention of adhesions after cesarean section; rather, it was found that these liquid barriers which impairs control of bleeding might cause an increase in adhesion formation. | en_US |
dc.description.sponsorship | Mutlu, A. E.; Cumhuriyet Üniversitesi, Tip Fakültesi, Kadin Hastaliklari Ve Do?um Anabilim Dali, Sivas, Turkey; email: dr.ahmetemutlu@gmail.com | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.5505/tjod.2012.53254 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Adhesion | en_US |
dc.subject | Cesarean section | en_US |
dc.subject | Low molecular weight heparin | en_US |
dc.subject | Methylene blue | en_US |
dc.subject | Rat | en_US |
dc.subject | Secondary fertility | en_US |
dc.title | Comparison of efficiency of Clexane® "enoxaparin sodium" and methylene blue in prevention of adhesions after cesarean section in pregnant rats [Gebe Ratlarda Sezaryen Operasyonu Sonrasi{dotless}, Adezyonlari{dotless}n Önlenmesinde Clexane® "Enoksapari?n Sodyum" ve Meti?len Mavi?si?'nin Etki?nli?kleri?ni?n Karşi{dotless}laşti{dotless}ri{dotless}lmasi{dotless}] | en_US |
dc.type | article | en_US |
dc.relation.journal | Turk Jinekoloji ve Obstetrik Dernegi Dergisi | en_US |
dc.contributor.department | Mutlu, A.E., Cumhuriyet Üniversitesi, Tip Fakültesi, Kadin Hastaliklari Ve Do?um Anabilim Dali, Sivas, Turkey -- Boztosun, A., Cumhuriyet Üniversitesi, Tip Fakültesi, Kadin Hastaliklari Ve Do?um Anabilim Dali, Sivas, Turkey -- Sümer, D., Cumhuriyet Üniversitesi, Tip Fakültesi, Kadin Hastaliklari Ve Do?um Anabilim Dali, Sivas, Turkey -- Yanik, A., Cumhuriyet Üniversitesi, Tip Fakültesi, Kadin Hastaliklari Ve Do?um Anabilim Dali, Sivas, Turkey | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.endpage | 223 | en_US |
dc.identifier.startpage | 216 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |