dc.contributor.author | Köten F. | |
dc.contributor.author | Öztop A.Y. | |
dc.contributor.author | Engin A. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:15:05Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:15:05Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 1992-2248 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/5031 | |
dc.description.abstract | The aim of this study was to determine the prevalence of anti-HBc positivity and presence of HBV DNA from anti-HBc positive found donations that are living in the city of Sivas, in Turkey. A total of 987 voluntary blood donors, admitted to blood centre of Cumhuriyet University Hospital Sivas, (Turkey) between February to June 2008 were included in this study. Presence of Anti-HBc was screened in all serum samples. Positive samples for Anti-HBc were tested for the presence of anti-HBs then anti-HBs-positive samples were investigated for HBcIgM, HBeAg and anti-HBe. All of the HBV serological markers were tested in all serum samples using ELISA method. The presence of HBV-DNA was determined quantitatively in serum samples of cases with isolated anti-HBc by real-time PCR. Anti-HBc total was established as positive 209 (21.1%) of the 987 blood donors. The isolated anti-HBc positivity was 15.8% and HBV DNA positivity in the blood donors was 0.1%. In conclusion, the risk of HBV transmission by transfusion in blood centers can reduce by routine screening for anti-HBc in addition to HBsAg screening and then investigating of HBV DNA in anti-HBc positive samples. ©2011 Academic Journals. | en_US |
dc.description.sponsorship | Öztop, A. Y.; Departments of Microbiology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey; email: ayoztop@gmail.com | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Blood donors | en_US |
dc.subject | HBV DNA | en_US |
dc.subject | Isolated anti-HBc | en_US |
dc.title | Investigation of the HBV DNA in isolated hepatitis B core antibody positive blood donors | en_US |
dc.type | article | en_US |
dc.relation.journal | Scientific Research and Essays | en_US |
dc.contributor.department | Köten, F., Institute of Health Sciences, Cumhuriyet University, Sivas, Turkey -- Öztop, A.Y., Departments of Microbiology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey -- Engin, A., Departments of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Cumhuriyet University Sivas, Turkey | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | 13 | en_US |
dc.identifier.endpage | 2723 | en_US |
dc.identifier.startpage | 2720 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |