dc.contributor.author | Arabaci F.I. | |
dc.contributor.author | Kaya A. | |
dc.contributor.author | Gültekin A. | |
dc.contributor.author | Iça?asio?lu F.D. | |
dc.contributor.author | Mutlu E.C. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:31:13Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:31:13Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 1300-0381 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/5111 | |
dc.description.abstract | Objective: In the present study, our aim was to determine the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) in children between 6 months-6 years old and to compare efficacy of oral Fe+2 (ferrous sulphate), Fe+3 (ferric polymaltose) and Fe+2 + Zn (ferrous fumarate+zinc sulphate) preparations in the treatment of iron deficiency anaemia. Material and Methods: The present study was conducted on 271 children (aged 6 months to 6 years) applying to our polyclinic. ID was diagnosed if hemoglobine (Hb) concentration was >11 g/dL and ferritin level was <12 ng/mL. Eighty one of the cases included in the study and having Hb <11 g/dL and ferritin <12 ng/mL were diagnosed with IDA. Those having IDA were divided into three groups. Those in the first group (n= 27), second group (n= 28) and third group (n= 26) were randomized to Fe+2, Fe +3 and Fe+2 + Zntreatments respectively. Iron treatment was administered on empty stomach as 3 x 2 mg/kg/day for 12 weeks. Results: The prevalences of ID and IDA were found to be 19.6% and 29.9%. When the groups were compared in terms of post-treatment Hb values, the increase in Hb values of those in Fe+2 group was statistically significantly higher than those observed in other groups. When the increase in Hb values of Fe+3 and Fe+2 + Zn groups were compared, there was no statistically significant difference. When mean corpuscular volume, serum iron, ferritin and reticulocyte response were compared to each other, the difference between Fe+2 and Fe+3 groups was statistically significant whereas no statistically significant difference was found between Fe+2 and Fe+2 + Zn or between Fe+2 + Zn and Fe+3 groups. Conclusion: The prevalences of ID and IDA detected in our study are similar to those reported in previous studies. We believe that oral administration of Fe+2 preparations alone in IDA is more efficient. Copyright © 2010 by Türkiye Klinikleri. | en_US |
dc.description.sponsorship | Kaya, A.; Cumhuriyet Üniversitesi Tip Fakültesi, Çocuk Sa?li?i ve Hastaliklari AD, Sivas, Turkey; email: dralikaya@gmail.com | en_US |
dc.language.iso | tur | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Child | en_US |
dc.subject | Ferrous sulfate | en_US |
dc.subject | Iron-deficiency anemia | en_US |
dc.subject | Zinc sulfate | en_US |
dc.title | Comparison of efficacies of divalent, trivalent irons and divalent iron plus zinc preparations in paediatric patients with iron deficiency anemia [Çocuklarda demir eksikli?i anemisinin tedavisinde +2 ve +3 de?erlikli demir i?çeren ve +2 de?erlikli demirle birlikte çinko i?çeren preperatlarin etkinliklerinin karşilaştirilmasi] | en_US |
dc.type | article | en_US |
dc.relation.journal | Turkiye Klinikleri Pediatri | en_US |
dc.contributor.department | Arabaci, F.I., Çocuk Sa?li?i ve Hastaliklari Klini?i, Yerköy Devlet Hastanesi, Yozgat, Turkey -- Kaya, A., Cumhuriyet Üniversitesi Tip Fakültesi, Çocuk Sa?li?i ve Hastaliklari AD, Sivas, Turkey -- Gültekin, A., Cumhuriyet Üniversitesi Tip Fakültesi, Çocuk Sa?li?i ve Hastaliklari AD, Sivas, Turkey -- Iça?asio?lu, F.D., Cumhuriyet Üniversitesi Tip Fakültesi, Çocuk Sa?li?i ve Hastaliklari AD, Sivas, Turkey, Çocuk Nöroloji BD, Cumhuriyet Üniversitesi Tip Fakültesi, Sivas, Turkey -- Mutlu, E.C., Cumhuriyet Üniversitesi Tip Fakültesi, Çocuk Sa?li?i ve Hastaliklari AD, Sivas, Turkey | en_US |
dc.identifier.volume | 19 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.endpage | 215 | en_US |
dc.identifier.startpage | 210 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |