Atherosclerosis in Behçet's Syndrome
dc.contributor.author | Seyahi E. | |
dc.contributor.author | Ugurlu S. | |
dc.contributor.author | Cumali R. | |
dc.contributor.author | Balci H. | |
dc.contributor.author | Ozdemir O. | |
dc.contributor.author | Melikoglu M. | |
dc.contributor.author | Hatemi G. | |
dc.contributor.author | Fresko I. | |
dc.contributor.author | Hamuryudan V. | |
dc.contributor.author | Yurdakul S. | |
dc.contributor.author | Yazici H. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:31:24Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:31:24Z | |
dc.date.issued | 2008 | |
dc.identifier.issn | 0049-0172 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.semarthrit.2007.09.009 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/5218 | |
dc.description.abstract | Objectives: We had the impression and preliminary evidence that atherosclerosis was not much increased in Behçet's syndrome (BS). Thus, we evaluated the presence of subclinical atherosclerosis in a sizeable group of patients with BS both with major organ involvement and mucocutaneous disease along with diseased and healthy controls. Methods: We studied 239 (162 M/ 77 F; mean age: 40.7 ± 7.0) patients with BS. Seventy-two (32 M/ 40 F) had only mucocutaneous and/or joint disease and 167 (130 M/ 37 F) had major organ involvement. Also 100 (24 M/ 76 F; mean age: 44.7 ± 7.1) patients with rheumatoid arthritis (RA), 74 (58 M/ 16 F; mean age: 39.4 ± 7.0) patients with ankylosing spondylitis (AS) and 156 (83 M/ 73 F; mean age: 39.2 ± 6.6) healthy controls (HC) were studied as the control groups. We used B-mode USG to assess the frequency of plaques and intima-media thickness (IMT) in the carotid and femoral arteries. Traditional atherosclerotic risk factors were also evaluated. Men and women were analyzed separately. Results: The frequency of plaques and the mean IMT in the carotid and femoral arteries were similar between patients with BS, AS and HC and also between the 2 subgroups of BS, among both men and women. Only men with RA were found to have significantly increased frequency of carotid artery plaques after adjustment for atherosclerotic risk factors. Conclusion: Increased atherosclerosis is not a prominent feature of BS, even among those patients with major organ involvement. © 2008 Elsevier Inc. All rights reserved. | en_US |
dc.description.sponsorship | Yazici, H.; Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey; email: hyazici@attglobal.net | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.1016/j.semarthrit.2007.09.009 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | atherosclerosis | en_US |
dc.subject | atherosclerotic plaques | en_US |
dc.subject | B-mode ultrasonography | en_US |
dc.subject | Behçet's syndrome | en_US |
dc.subject | carotid artery | en_US |
dc.subject | femoral artery | en_US |
dc.subject | intima-media thickness | en_US |
dc.title | Atherosclerosis in Behçet's Syndrome | en_US |
dc.type | article | en_US |
dc.relation.journal | Seminars in Arthritis and Rheumatism | en_US |
dc.contributor.department | Seyahi, E., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey -- Ugurlu, S., Department of Internal Medicine, Medical Faculty, Cumhuriyet University, Sivas, Turkey -- Cumali, R., Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey -- Balci, H., Central Research Laboratory, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey -- Ozdemir, O., Yorum Consultancy Ltd, Istanbul, Turkey -- Melikoglu, M., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey -- Hatemi, G., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey -- Fresko, I., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey -- Hamuryudan, V., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey -- Yurdakul, S., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey -- Yazici, H., Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, Istanbul, Turkey | en_US |
dc.identifier.volume | 38 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.endpage | 12 | en_US |
dc.identifier.startpage | 1 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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