Potassium carbonate mediated one-pot synthesis and antimicrobial activities of 2-alkoxy-4-(aryl)-5H-indeno[1,2-b]pyridine-3-carbonitriles
dc.contributor.author | Öztürk S. | |
dc.contributor.author | Gürdere M.B. | |
dc.contributor.author | Gezegen H. | |
dc.contributor.author | Ceylan M. | |
dc.contributor.author | Budak Y. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:31:42Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:31:42Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1307-6175 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/5319 | |
dc.description | ACG Publications | en_US |
dc.description.abstract | 2-Alkoxy-4-(aryl)-5H-indeno[1,2-b]pyridine-3-carbonitriles (3a-e and 4a-e) were synthesized via multicomponent reaction from 2-aryl-methylidineindan-1-ones (1a-e), malononitrile and K2CO3 in ethanol and/or methanol. The structures of obtained compounds (3a-e and 4a-e) were characterized using the spectroscopic methods (NMR, IR) and elemental analysis. Addition, the in vitro antimicrobial activities of compounds (3a-e) were tested against the five human pathogenic bacteria. Penicillin G and Ceftriaxone antibiotics were used as positive control. The results were given as MIC values (minimum inhibition concentration), and compounds 3b-d showed very high activity against Escherichia coli 111. © 2016 ACG Publications. | en_US |
dc.description.sponsorship | Budak, Y.; Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa UniversityTurkey; email: yakup.budak@gop.edu.tr | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | 1-Indanone | en_US |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Malononitrile | en_US |
dc.subject | Pyridine-3-carbonitrile | en_US |
dc.title | Potassium carbonate mediated one-pot synthesis and antimicrobial activities of 2-alkoxy-4-(aryl)-5H-indeno[1,2-b]pyridine-3-carbonitriles | en_US |
dc.type | article | en_US |
dc.relation.journal | Organic Communications | en_US |
dc.contributor.department | Öztürk, S., Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University, Tokat, 60250, Turkey -- Gürdere, M.B., Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University, Tokat, 60250, Turkey -- Gezegen, H., Department of Nutrition and Dietetics, Faculty of Health Science, Cumhuriyet University, Sivas, Turkey -- Ceylan, M., Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University, Tokat, 60250, Turkey -- Budak, Y., Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University, Tokat, 60250, Turkey | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.endpage | 132 | en_US |
dc.identifier.startpage | 125 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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