| dc.contributor.author | Kocyigit, Umit Muhammet | |
| dc.date.accessioned | 2019-07-27T12:10:23Z | |
| dc.date.accessioned | 2019-07-28T09:37:21Z | |
| dc.date.available | 2019-07-27T12:10:23Z | |
| dc.date.available | 2019-07-28T09:37:21Z | |
| dc.date.issued | 2019 | |
| dc.identifier.issn | 1018-4619 | |
| dc.identifier.issn | 1610-2304 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12418/6040 | |
| dc.description | WOS: 000461270800022 | en_US |
| dc.description.abstract | This study aims to examine the inhibitory effect of Quebecol on alpha-glycosidase and alpha-amylase enzyme activities in comparison with acarbose as a standard. IC50 amounts were obtained by using the Quebecol-Induced Activity (%) - [Quebecol] graph and the Lineweaver-Burk graph. The IC50 values obtained with Quebecol were 28.56 nM for alpha-glycosidase and 211.82 nM for alpha-amylase, while the mean K-i value was 8.04 nM for alpha-glycosidase. The results of our study are expected to contribute to pharmaceutical research and pharmacological applications by providing insight into the biological effects of Quebecol. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | PARLAR SCIENTIFIC PUBLICATIONS (P S P) | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Quebecol | en_US |
| dc.subject | alpha-glycosidase | en_US |
| dc.subject | alpha-amylase | en_US |
| dc.subject | enzyme inhibition | en_US |
| dc.title | ANTIDIABETIC PROPERTIES OF QUEBECOL AS NATURAL PHENOLIC COMPOUND: alpha -GLYCOSIDASE AND alpha -AMYLASE METABOLIC ENZYMES INHIBITION PROPERTIES | en_US |
| dc.type | article | en_US |
| dc.relation.journal | FRESENIUS ENVIRONMENTAL BULLETIN | en_US |
| dc.contributor.department | [Kocyigit, Umit Muhammet] Sivas Cumhuriyet Univ, Vocat Sch Hlth Serv, TR-58140 Sivas, Turkey | en_US |
| dc.identifier.volume | 28 | en_US |
| dc.identifier.issue | 2A | en_US |
| dc.identifier.endpage | 1228 | en_US |
| dc.identifier.startpage | 1224 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
