dc.contributor.author | Oymak, Tulay | |
dc.contributor.author | Ertas, Nusret | |
dc.contributor.author | Tamer, Ugur | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:38:20Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:38:20Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1304-530X | |
dc.identifier.uri | https://dx.doi.org/10.4274/tjps.02986 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/6319 | |
dc.description | WOS: 000433580100007 | en_US |
dc.description.abstract | Objectives: To describe a method for the determination of urea in blood serum using urease enzyme and 3-MPA-capped CdTe quantum dots. Materials and Methods: The method is based on the increase in pH of the solution as a result of the reaction between urea and urease, which causes an increase in the phosphorescence signal of MPA-CdTe quantum dots in the pH range of 2.5-5.0. Under the optimum conditions, the linear range of urea was 0.016-0.16 mM (1-10 mg/L) and the limit of detection based on 3 s/b was calculated as 0.003 mM (0.17 mg/L). The relative standard deviation was calculated as 3.4% at 4 mg/L urea concentration (n=7). Results: The method was applied to human serum samples. The same samples were analyzed by an independent laboratory and the results were not statistically different, at 95% confidence level (F test). Conclusion: The proposed method does not need sample pretreatment, is simple, selective, and cost-effective for the determination of urea in serum samples. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | TURKISH PHARMACISTS ASSOC | en_US |
dc.relation.isversionof | 10.4274/tjps.02986 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Phosphorescent quantum dots | en_US |
dc.subject | MPA-capped CdTe | en_US |
dc.subject | urea | en_US |
dc.title | Use of Water Soluble and Phosphorescent MPA-capped CdTe Quantum Dots for the Detection of Urea | en_US |
dc.type | article | en_US |
dc.relation.journal | TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES | en_US |
dc.contributor.department | [Oymak, Tulay] Cumhuriyet Univ, Fac Pharm, Dept Analyt Chem, Sivas, Turkey -- [Ertas, Nusret -- Tamer, Ugur] Gazi Univ, Fac Pharm, Dept Analyt Chem, Ankara, Turkey | en_US |
dc.contributor.authorID | ERTAS, NUSRET -- 0000-0002-9770-3292 | en_US |
dc.identifier.volume | 15 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.endpage | 49 | en_US |
dc.identifier.startpage | 44 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |