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dc.contributor.authorErdem, Gokmen U.
dc.contributor.authorDogan, Mutlu
dc.contributor.authorSakin, Abdullah
dc.contributor.authorOruc, Zeynep
dc.contributor.authorYaman, Emel
dc.contributor.authorCinkir, Havva Yesil
dc.contributor.authorUysal, Mukremin
dc.contributor.authorBozkurt, Oktay
dc.contributor.authorOzturk, Banu
dc.contributor.authorAytekin, Aydin
dc.contributor.authorOzcelik, Melike
dc.contributor.authorBahceci, Aykut
dc.contributor.authorCakiroglu, Umut
dc.contributor.authorTurhal, Serdar
dc.contributor.authorSahin, Suleyman
dc.contributor.authorUncu, Dogan
dc.contributor.authorZengin, Nurullah
dc.descriptionWOS: 000430115300010en_US
dc.descriptionPubMed ID: 29558755en_US
dc.description.abstractObjectives: The clinicopathological characteristics, treatment modalities, and effects on the prognosis of pure squamous cell carcinoma (SqCC) and adenocarcinoma (AC) were evaluated. Materials and Methods: 86 patients with pure SqCC and AC bladder cancer were evaluated retrospectively. Results: Of the 86 patients, 51 had SqCC and 35 had AC. No differences in clinicopathological characteristics were observed between patients with AC and SqCC, except for the prevalence of T4 disease (28.6% vs. 51.0%, respectively). In multivariate analysis, older age, stage IV disease, and Eastern Cooperative Oncology Group (ECOG) performance status (> 2) were predictive of a poor overall survival (OS). The median OS was significantly longer for stage I-III patients (82.9 months) treated with surgery +/- chemotherapy (CT) +/- radiotherapy (RT) than for those treated with transurethral resection +/- CT +/- RT (24.3 months) (P = 0.007). The median OS of patients with SqCC and AC who were given platinum-based CT for metastasis was 7.7 and 30.3 months, respectively. Conclusions: Advanced age, stage IV disease, and poor ECOG performance status were factors associated with a poor prognosis. Surgery +/- CT +/- RT resulted in significantly better OS, except in stage IV disease. Patients with metastatic AC had better response rates with platinum- based CT. (c) 2018 S. Karger GmbH, Freiburgen_US
dc.subjectBladder canceren_US
dc.subjectSquamous cell carcinomaen_US
dc.titleNon-Urothelial Bladder Cancer: Comparison of Clinicopathological and Prognostic Characteristics in Pure Adenocarcinoma and Non-Bilharzial Squamous Cell Carcinoma of the Bladderen_US
dc.contributor.department[Erdem, Gokmen U.] Kocaeli Derince Training & Res Hosp, Dept Med Oncol, TR-41310 Ssk Hst, Kocaeli, Turkey -- [Dogan, Mutlu -- Uncu, Dogan -- Zengin, Nurullah] Ankara Numune Training & Res Hosp, Dept Med Oncol, Ankara, Turkey -- [Sakin, Abdullah] Okmeydani Training & Res Hosp, Dept Med Oncol, Istanbul, Turkey -- [Oruc, Zeynep] Dicle Univ, Fac Med, Dept Med Oncol, Diyarbakir, Turkey -- [Yaman, Emel] Mersin Univ, Fac Med, Dept Med Oncol, Mersin, Turkey -- [Cinkir, Havva Yesil] Dr Abdurrahman Yurtaslan Ankara Oncol Training &, Dept Med Oncol, Ankara, Turkey -- [Uysal, Mukremin] Afyon Kocatepe Univ, Fac Med, Dept Med Oncol, Afyon, Turkey -- [Bozkurt, Oktay] Erciyes Univ, Fac Med, Dept Med Oncol, Kayseri, Turkey -- [Ozturk, Banu] Antalya Training & Res Hosp, Dept Med Oncol, Antalya, Turkey -- [Aytekin, Aydin] Gazi Univ, Fac Med, Dept Med Oncol, Ankara, Turkey -- [Ozcelik, Melike] Kartal Educ & Res Hosp, Dept Med Oncol, Istanbul, Turkey -- [Bahceci, Aykut] Cumhuriyet Univ, Fac Med, Dept Med Oncol, Sivas, Turkey -- [Cakiroglu, Umut] Pamukkale Univ, Fac Med, Dept Med Oncol, Denizli, Turkey -- [Turhal, Serdar] Anadolu Med Ctr, Dept Med Oncol, Kocaeli, Turkey -- [Sahin, Suleyman] Diskapi Yildirim Beyazit Educ & Training Hosp, Dept Med Oncol, Ankara, Turkeyen_US
dc.contributor.authorIDSAKIN, abdullah -- 0000-0003-2538-8569; Cakiroglu, Umut -- 0000-0002-3274-2565en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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