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dc.contributor.authorDurmus, Kasim
dc.contributor.authorEngin, Aynur
dc.contributor.authorKaratas, Tuba Dogan
dc.contributor.authorGozel, Mustafa Gokhan
dc.contributor.authorAltuntas, Emine Elif
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:41:07Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:41:07Z
dc.date.issued2017
dc.identifier.issn0146-6615
dc.identifier.issn1096-9071
dc.identifier.urihttps://dx.doi.org/10.1002/jmv.24727
dc.identifier.urihttps://hdl.handle.net/20.500.12418/6767
dc.descriptionWOS: 000398893900004en_US
dc.descriptionPubMed ID: 27813123en_US
dc.description.abstractCrimean-Congo hemorrhagic fever (CCHF) is an important health problem in Turkey. Number of studies on symptoms of ear nose throat system and indicating whether or not the organs are affected in patients with CCHF is limited. The aim of the present study was to investigate whether CCHF infections caused any change in nasal physiology in adult patients or not by using saccharin transit time (STT) and nasal symptom scoring. Twenty subjects with laboratory-confirmed diagnosis of CCHF and 28 healthy control subjects were included in the present study. A saccharin test was used to evaluate nasal mucociliary clearance time (NMCT) and the nasal symptom scoring used in allergic rhinitis was modified and used to examine the symptoms of the patients. The average STT of CCHF and control groups were 472.70 +/- 151.58 and 276.07 +/- 89.65sec, respectively. The difference between them was statistically significant (P=0.00, P<0.05). When those in CCHF group were classified according to timing of the test, STT average of those undergoing the test on the 1st-3rd days (n=10) and 4th-6th (n=10) days was 547.00 +/- 154.37 and 398.40 +/- 111.39sec, respectively. The difference between them was statistically significant (P=0.024; P<0.05). The results of the present study showed that NMCT prolonged in adult patients with CCHF compared to those in the control group despite the fact that it was within normal limits. For these reasons, clinicians should follow-up CCHF patients more closely for respiratory tract diseases and sinonasal and middle ear infections. J. Med. Virol. 89:960-965, 2017. (c) 2016 Wiley Periodicals, Inc.en_US
dc.language.isoengen_US
dc.publisherWILEYen_US
dc.relation.isversionof10.1002/jmv.24727en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCrimean-Congo hemorrhagic feveren_US
dc.subjectnasal mucociliary clearance timeen_US
dc.subjectnasal physiologyen_US
dc.subjectnasal symptom scoringen_US
dc.titleDetermination of nasal mucociliary clearance time and nasal symptom in patients with Crimean-Congo hemorrhagic feveren_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF MEDICAL VIROLOGYen_US
dc.contributor.department[Durmus, Kasim -- Karatas, Tuba Dogan -- Altuntas, Emine Elif] Cumhuriyet Univ, Dept Otolaryngol, Fac Med, TR-58140 Sivas, Turkey -- [Engin, Aynur -- Gozel, Mustafa Gokhan] Cumhuriyet Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Sivas, Turkeyen_US
dc.contributor.authorIDGozel, Mustafa Gokhan -- 0000-0001-5187-7388en_US
dc.identifier.volume89en_US
dc.identifier.issue6en_US
dc.identifier.endpage965en_US
dc.identifier.startpage960en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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